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1A8697

The utilization of biocompatible macroporous hydrogels containing cell cultures in the therapy of spinal cord injuries

Public support

  • Provider

    Ministry of Health

  • Programme

    Population Health (National programme of research)

  • Call for proposals

    Zdraví obyvatel 2 (SMZ020051A)

  • Main participants

  • Contest type

    VS - Public tender

  • Contract ID

    1A8697-5/2005

Alternative language

  • Project name in Czech

    Využití biokompatibilních makroporézních hydrogelů obsahujících buněčné kultury k terapii míšního poranění

  • Annotation in Czech

    Projekt počítá s využitím biokompatibilních makroporézních hydrogelů obohacených o vhodné buněčné kultury k náhradám strukturálních defektů tkání centrálního nervového systému, zejména postraumatických pseudocyst vzniklých po míšním poranění. Vytvoření trojrozměrných struktur osázených kmenovými buňkami by mohlo být řešením pro obnovení regenerace míšní tkáně u chronických pacientů.

Scientific branches

  • R&D category

    NV - Nonindustrial research (Applied research excluded Industrial research)

  • CEP classification - main branch

    FJ - Surgery including transplantology

  • CEP - secondary branch

    EI - Biotechnology and bionics

  • CEP - another secondary branch

  • OECD FORD - equivalent branches <br>(according to the <a href="http://www.vyzkum.cz/storage/att/E6EF7938F0E854BAE520AC119FB22E8D/Prevodnik_oboru_Frascati.pdf">converter</a>)

    20801 - Environmental biotechnology<br>20802 - Bioremediation, diagnostic biotechnologies (DNA chips and biosensing devices) in environmental management<br>20803 - Environmental biotechnology related ethics<br>20901 - Industrial biotechnology<br>20902 - Bioprocessing technologies (industrial processes relying on biological agents to drive the process) biocatalysis, fermentation<br>20903 - Bioproducts (products that are manufactured using biological material as feedstock) biomaterials, bioplastics, biofuels, bioderived bulk and fine chemicals, bio-derived novel materials<br>30212 - Surgery<br>30213 - Transplantation<br>30401 - Health-related biotechnology<br>30402 - Technologies involving the manipulation of cells, tissues, organs or the whole organism (assisted reproduction)<br>30403 - Technologies involving identifying the functioning of DNA, proteins and enzymes and how they influence the onset of disease and maintenance of well-being (gene-based diagnostics and therapeutic interventions [pharmacogenomics, gene-based therapeutics])<br>30404 - Biomaterials (as related to medical implants, devices, sensors)<br>30405 - Medical biotechnology related ethics<br>40401 - Agricultural biotechnology and food biotechnology<br>40402 - GM technology (crops and livestock), livestock cloning, marker assisted selection, diagnostics (DNA chips and biosensing devices for the early/accurate detection of diseases) biomass feedstock production technologies, biopharming<br>40403 - Agricultural biotechnology related ethics

Completed project evaluation

  • Provider evaluation

    V - Vynikající výsledky projektu (s mezinárodním významem atd.)

  • Project results evaluation

    authors have chosen from several materials HPMA-RGD hydrogels and the most suitable candidate for stem cell carrier. they have shown that in chronic spinal cord injury cells can survive in the hydrogels for 6 months and improve functional outcome in rats

Solution timeline

  • Realization period - beginning

    Aug 1, 2005

  • Realization period - end

    Dec 31, 2009

  • Project status

    U - Finished project

  • Latest support payment

    Dec 18, 2009

Data delivery to CEP

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

  • Data delivery code

    CEP10-MZ0-1A-U/02:2

  • Data delivery date

    Aug 20, 2010

Finance

  • Total approved costs

    4,604 thou. CZK

  • Public financial support

    4,590 thou. CZK

  • Other public sources

    0 thou. CZK

  • Non public and foreign sources

    12 thou. CZK