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1A8709

In vitro separation and molecular analysis of graft-versus-host-specific and graft-versus-tumor-specific T cells

Public support

  • Provider

    Ministry of Health

  • Programme

    Population Health (National programme of research)

  • Call for proposals

    Zdraví obyvatel 2 (SMZ020051A)

  • Main participants

  • Contest type

    VS - Public tender

  • Contract ID

    1A8709-5/2005

Alternative language

  • Project name in Czech

    Rozlišení a molekulární analýza aloreaktivních a nádorově-specifických T lymfocytů in vitro

  • Annotation in Czech

    Náplní projektu je identifikace, rozlišení a molekulární analýza individuálních klonů T lymfocytů zodpovědných za rozvoj reakce štěpu proti hostiteli a reakce štěpu proti nádoru s cílem potlačení aloreaktivity a potenciace protinádorové reaktivity.

Scientific branches

  • R&D category

    NV - Nonindustrial research (Applied research excluded Industrial research)

  • CEP classification - main branch

    FD - Oncology and haematology

  • CEP - secondary branch

    FN - Epidemiology, infection diseases and clinical immunology

  • CEP - another secondary branch

    FG - Paediatrics

  • OECD FORD - equivalent branches <br>(according to the <a href="http://www.vyzkum.cz/storage/att/E6EF7938F0E854BAE520AC119FB22E8D/Prevodnik_oboru_Frascati.pdf">converter</a>)

    30204 - Oncology<br>30205 - Hematology<br>30209 - Paediatrics<br>30302 - Epidemiology<br>30303 - Infectious Diseases

Completed project evaluation

  • Provider evaluation

    V - Vynikající výsledky projektu (s mezinárodním významem atd.)

  • Project results evaluation

    Anti CD25 imumotoxin evoked selective depletion of donor aloreactive clones T lymfocyt. Proposed safe way of implementing alogen transplantation of hematopoetic cells may indicate a shift in the extension of the indications to alogennic transplantations

Solution timeline

  • Realization period - beginning

    Aug 1, 2005

  • Realization period - end

    Dec 31, 2009

  • Project status

    U - Finished project

  • Latest support payment

    Dec 18, 2009

Data delivery to CEP

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

  • Data delivery code

    CEP10-MZ0-1A-U/02:2

  • Data delivery date

    Aug 20, 2010

Finance

  • Total approved costs

    8,356 thou. CZK

  • Public financial support

    8,036 thou. CZK

  • Other public sources

    45 thou. CZK

  • Non public and foreign sources

    135 thou. CZK