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Research and development of a new type of electrochemical biosensor for the detection of nucleotide sequences in DNA and of genotoxic agents in the environment.

Public support

  • Provider

    Ministry of Industry and Trade

  • Programme

    ADVANCEMENT (National programme of research)

  • Call for proposals

    POKROK 1 (SMPO200430001)

  • Main participants

  • Contest type

    VS - Public tender

  • Contract ID

    1H-PK/42

Alternative language

  • Project name in Czech

    Výzkum a vývoj nového typu elektrochemického biosenzoru pro detekci sekvence nukleotidů v DNA a genotoxických agens v prostředí.

  • Annotation in Czech

    V současné době jsou stále více využívány zařízení (senzory, čipy apod.) umožňující rychlé zjišťování velkého počtu sekvencí nukleotidů v DNA i RNA, založené na optických metodách. Záměren projektu je doplnit optickou detekci, výhodnější a levnější detekcí elektrochemickou.

Scientific branches

  • R&D category

    ZV - Basic research

  • CEP classification - main branch

    EI - Biotechnology and bionics

  • CEP - secondary branch

    EB - Genetics and molecular biology

  • CEP - another secondary branch

  • OECD FORD - equivalent branches <br>(according to the <a href="http://www.vyzkum.cz/storage/att/E6EF7938F0E854BAE520AC119FB22E8D/Prevodnik_oboru_Frascati.pdf">converter</a>)

    10603 - Genetics and heredity (medical genetics to be 3)<br>10604 - Reproductive biology (medical aspects to be 3)<br>10605 - Developmental biology<br>10608 - Biochemistry and molecular biology<br>10609 - Biochemical research methods<br>20801 - Environmental biotechnology<br>20802 - Bioremediation, diagnostic biotechnologies (DNA chips and biosensing devices) in environmental management<br>20803 - Environmental biotechnology related ethics<br>20901 - Industrial biotechnology<br>20902 - Bioprocessing technologies (industrial processes relying on biological agents to drive the process) biocatalysis, fermentation<br>20903 - Bioproducts (products that are manufactured using biological material as feedstock) biomaterials, bioplastics, biofuels, bioderived bulk and fine chemicals, bio-derived novel materials<br>30101 - Human genetics<br>30401 - Health-related biotechnology<br>30402 - Technologies involving the manipulation of cells, tissues, organs or the whole organism (assisted reproduction)<br>30403 - Technologies involving identifying the functioning of DNA, proteins and enzymes and how they influence the onset of disease and maintenance of well-being (gene-based diagnostics and therapeutic interventions [pharmacogenomics, gene-based therapeutics])<br>30404 - Biomaterials (as related to medical implants, devices, sensors)<br>30405 - Medical biotechnology related ethics<br>40401 - Agricultural biotechnology and food biotechnology<br>40402 - GM technology (crops and livestock), livestock cloning, marker assisted selection, diagnostics (DNA chips and biosensing devices for the early/accurate detection of diseases) biomass feedstock production technologies, biopharming<br>40403 - Agricultural biotechnology related ethics

Completed project evaluation

  • Provider evaluation

    U - Uspěl podle zadání (s publikovanými či patentovanými výsledky atd.)

  • Project results evaluation

    New types of electrochemical sensors for DNA, proteins and genotoxic species, novel approaches to DNA labeling and sensing of DNA sequences, mutations and DNA damage were developed.

Solution timeline

  • Realization period - beginning

    Sep 1, 2004

  • Realization period - end

    Jun 30, 2007

  • Project status

    U - Finished project

  • Latest support payment

    Apr 20, 2007

Data delivery to CEP

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

  • Data delivery code

    CEP08-MPO-1H-U/01:1

  • Data delivery date

    Jun 20, 2008

Finance

  • Total approved costs

    14,864 thou. CZK

  • Public financial support

    7,403 thou. CZK

  • Other public sources

    0 thou. CZK

  • Non public and foreign sources

    7,462 thou. CZK