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1M0538

Center for Cell Therapy and Tissue Repair

Project goals

Cell therapy provides an alternative treatment for degenerative and civilization-related diseases, including neurological. The aim of cell therapy, especially using stem cells, is to replace, repair and improve the function of damaged tissue. We will achthis aim by implanting cells into a target organ in sufficient numbers and quality to initiate functional recovery. Biocompatible hydrogels and their ability to support the recovery of damaged tissue and to increase the possibility ofregeneration forms an integral part of the project. Our aim is to perform preclinical tests and to introduce the methods used into clinical practice.

Keywords

stem cellshydrogelspolymersinjurybrainspinal cordnuclear magnetic resonanceembryohepatocytesdiabetes melittus

Public support

  • Provider

    Ministry of Education, Youth and Sports

  • Programme

    The research centres (National research program)

  • Call for proposals

    Výzkumná centra 1 (SMSM2005001M1)

  • Main participants

  • Contest type

    VS - Public tender

  • Contract ID

    14/2010-31

Alternative language

  • Project name in Czech

    Centrum buněčné terapie a tkáňových náhrad

  • Annotation in Czech

    Buněčná terapie je alternativou pro léčení degenerativních a civilizačních chorob, včetně nervových. Cílem buněčné terapie, zvl. pomocí kmenových buněk, je nahradit, opravit a zlepšit funkci poškozené tkáně. Toho chceme dosáhnout pomocí implantaceizolovaných a dobře charakterizovaných buněk do cílového orgánu v dostatečném počtu a kvalitě tak, aby byly schopny navodit návrat funkce. Součástí projektu je výzkum biokompatibilních hydrogelů a jejich schopností podpořit obnovu a nahradit poškozenoutkáň a zvýšit možnost regenerace. Cílem projektu je provedení klinických zkoušek a uplatnit oveřené postupy pro užití v klinické praxi.

Scientific branches

  • R&D category

    AP - Applied research

  • CEP classification - main branch

    FH - Neurology, neuro-surgery, nuero-sciences

  • CEP - secondary branch

    FJ - Surgery including transplantology

  • CEP - another secondary branch

    FI - Traumatology and orthopaedics

  • 30103 - Neurosciences (including psychophysiology)
    30210 - Clinical neurology
    30211 - Orthopaedics
    30212 - Surgery
    30213 - Transplantation

Completed project evaluation

  • Provider evaluation

    V - Vynikající výsledky projektu (s mezinárodním významem atd.)

  • Project results evaluation

    Results of high scientific quality were obtained in the field of cellular resources, in experimental models of cellular therapy, in the field of biomaterials and in clinical studies. Some of them were patented and/or submitted as certified methodologies.The center has significantly contributed to education of students. The objectives of the programme were achieved at a high quality level.

Solution timeline

  • Realization period - beginning

    Jan 1, 2005

  • Realization period - end

    Dec 31, 2011

  • Project status

    U - Finished project

  • Latest support payment

    Feb 3, 2011

Data delivery to CEP

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

  • Data delivery code

    CEP12-MSM-1M-U/01:1

  • Data delivery date

    Jul 3, 2012

Finance

  • Total approved costs

    241,173 thou. CZK

  • Public financial support

    216,376 thou. CZK

  • Other public sources

    0 thou. CZK

  • Non public and foreign sources

    24,797 thou. CZK

Recognised costs

241 173 CZK thou.

Public support

216 376 CZK thou.

0%


Provider

Ministry of Education, Youth and Sports

CEP

FH - Neurology, neuro-surgery, nuero-sciences

Solution period

01. 01. 2005 - 31. 12. 2011