The design and synthesis of novel ergopeptides with migraine-prophylactic properties
Public support
Provider
Ministry of Education, Youth and Sports
Programme
Programme of regional and international cooperation in R&D (National programme of research)
Call for proposals
Regionální a mezinárodní spolupráce ve výzkumu 1 (SMSM2004001P1)
Main participants
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Contest type
VS - Public tender
Contract ID
—
Alternative language
Project name in Czech
Formulace a syntéza nových ergopeptidů s profylaktickými účinky
Annotation in Czech
vývoj nových farmaceutických preparátů, profylaxe migrény, předklinické testy, nove rgopeptiny
Scientific branches
R&D category
NV - Nonindustrial research (Applied research excluded Industrial research)
CEP classification - main branch
FR - Pharmacology and apothecary chemistry
CEP - secondary branch
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CEP - another secondary branch
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OECD FORD - equivalent branches <br>(according to the <a href="http://www.vyzkum.cz/storage/att/E6EF7938F0E854BAE520AC119FB22E8D/Prevodnik_oboru_Frascati.pdf">converter</a>)
30104 - Pharmacology and pharmacy
Completed project evaluation
Provider evaluation
V - Vynikající výsledky projektu (s mezinárodním významem atd.)
Project results evaluation
There has been synthesized 74 new ergot derivates, 60 of these were tested for neuropharmacological activityy on animal models that allow the characterisation of various receptor types.
Solution timeline
Realization period - beginning
Jan 1, 2004
Realization period - end
Jan 1, 2006
Project status
U - Finished project
Latest support payment
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Data delivery to CEP
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data delivery code
CEP07-MSM-1P-U/01:1
Data delivery date
Jun 15, 2007
Finance
Total approved costs
9,600 thou. CZK
Public financial support
4,800 thou. CZK
Other public sources
0 thou. CZK
Non public and foreign sources
4,800 thou. CZK