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Positional cloning of a gene on chromosome 10 that is responsible for hypertension and metabolic defects in the spontaneously hypertensive rat

Public support

  • Provider

    Ministry of Education, Youth and Sports

  • Programme

    Programme of regional and international cooperation in R&D (National programme of research)

  • Call for proposals

    Regionální a mezinárodní spolupráce ve výzkumu 2 (SMSM2004001P2)

  • Main participants

  • Contest type

    VS - Public tender

  • Contract ID

    30 324/2004-32

Alternative language

  • Project name in Czech

    Poziční klonování genu na chromozomu 10, odpovědného za hypertenzi a metabolické poruchy u spontánně hypertenzních potkanů

  • Annotation in Czech

    zmapování lokusů kvantitativních znaků (QTL) regulujících tlak a metabolické fenotypy na chromozomu 10 u kmene SHR - 5cm dlouhé intervaly

Scientific branches

  • R&D category

    NV - Nonindustrial research (Applied research excluded Industrial research)

  • CEP classification - main branch

    ED - Physiology

  • CEP - secondary branch

  • CEP - another secondary branch

  • OECD FORD - equivalent branches <br>(according to the <a href="http://www.vyzkum.cz/storage/att/E6EF7938F0E854BAE520AC119FB22E8D/Prevodnik_oboru_Frascati.pdf">converter</a>)

    30105 - Physiology (including cytology)

Completed project evaluation

  • Provider evaluation

    V - Vynikající výsledky projektu (s mezinárodním významem atd.)

  • Project results evaluation

    Definitive evidence for the identity of Hcll (hepatic cholesterol level 1) QTL on chromosome 10 with mutant Srebfl (sterol regulatory element binding protein 1) was obtained in the spontaneously hypertensive rat.

Solution timeline

  • Realization period - beginning

    Jan 1, 2005

  • Realization period - end

    Dec 31, 2008

  • Project status

    U - Finished project

  • Latest support payment

    Feb 15, 2008

Data delivery to CEP

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

  • Data delivery code

    CEP09-MSM-1P-U/01:1

  • Data delivery date

    Jun 25, 2009

Finance

  • Total approved costs

    1,410 thou. CZK

  • Public financial support

    1,410 thou. CZK

  • Other public sources

    0 thou. CZK

  • Non public and foreign sources

    0 thou. CZK