Intracellular and extracellular targets for antitumor activity and toxicity of ruthenium complexex
Project goals
complexex of rhutenium as a new class of promising cytostatics effective in tumor cell resistant to platinum cytostatics
Keywords
intracellular and extracellular targetsantitumor activitytoxicity of ruthenium complexexcytostatics
Public support
Provider
Ministry of Education, Youth and Sports
Programme
Programme of regional and international cooperation in R&D (National programme of research)
Call for proposals
Regionální a mezinárodní spolupráce ve výzkumu 2 (SMSM2004001P2)
Main participants
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Contest type
VS - Public tender
Contract ID
—
Alternative language
Project name in Czech
Vnitrobuněčná a mimobuněčná cílová místa protinádorové aktivity a toxicity komplexů ruthenia
Annotation in Czech
komplexy ruthenia jako nová třída slibných cytostatik účinných i v nádorových buňkách resistentních vůči cytostatikům platinovým
Scientific branches
Completed project evaluation
Provider evaluation
U - Uspěl podle zadání (s publikovanými či patentovanými výsledky atd.)
Project results evaluation
Interactions of selected antitumor reuthenium complexes with DNA have been described. The results allowed improving structure-prarmacological relationships of ruthenium complexes.
Solution timeline
Realization period - beginning
Jan 1, 2005
Realization period - end
Jan 1, 2006
Project status
U - Finished project
Latest support payment
—
Data delivery to CEP
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data delivery code
CEP07-MSM-1P-U/01:1
Data delivery date
Jun 15, 2007
Finance
Total approved costs
705 thou. CZK
Public financial support
522 thou. CZK
Other public sources
0 thou. CZK
Non public and foreign sources
183 thou. CZK
Basic information
Recognised costs
705 CZK thou.
Public support
522 CZK thou.
74%
Provider
Ministry of Education, Youth and Sports
CEP
FR - Pharmacology and apothecary chemistry
Solution period
01. 01. 2005 - 01. 01. 2006