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Intracellular and extracellular targets for antitumor activity and toxicity of ruthenium complexex

Public support

  • Provider

    Ministry of Education, Youth and Sports

  • Programme

    Programme of regional and international cooperation in R&D (National programme of research)

  • Call for proposals

    Regionální a mezinárodní spolupráce ve výzkumu 2 (SMSM2004001P2)

  • Main participants

  • Contest type

    VS - Public tender

  • Contract ID

Alternative language

  • Project name in Czech

    Vnitrobuněčná a mimobuněčná cílová místa protinádorové aktivity a toxicity komplexů ruthenia

  • Annotation in Czech

    komplexy ruthenia jako nová třída slibných cytostatik účinných i v nádorových buňkách resistentních vůči cytostatikům platinovým

Scientific branches

  • R&D category

    NV - Nonindustrial research (Applied research excluded Industrial research)

  • CEP classification - main branch

    FR - Pharmacology and apothecary chemistry

  • CEP - secondary branch

  • CEP - another secondary branch

  • OECD FORD - equivalent branches <br>(according to the <a href="http://www.vyzkum.cz/storage/att/E6EF7938F0E854BAE520AC119FB22E8D/Prevodnik_oboru_Frascati.pdf">converter</a>)

    30104 - Pharmacology and pharmacy

Completed project evaluation

  • Provider evaluation

    U - Uspěl podle zadání (s publikovanými či patentovanými výsledky atd.)

  • Project results evaluation

    Interactions of selected antitumor reuthenium complexes with DNA have been described. The results allowed improving structure-prarmacological relationships of ruthenium complexes.

Solution timeline

  • Realization period - beginning

    Jan 1, 2005

  • Realization period - end

    Jan 1, 2006

  • Project status

    U - Finished project

  • Latest support payment

Data delivery to CEP

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

  • Data delivery code

    CEP07-MSM-1P-U/01:1

  • Data delivery date

    Jun 15, 2007

Finance

  • Total approved costs

    705 thou. CZK

  • Public financial support

    522 thou. CZK

  • Other public sources

    0 thou. CZK

  • Non public and foreign sources

    183 thou. CZK