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2B06077

High throughput analysis of chromatin structure for development of novel diagnostic and therapeutic approaches in cancer.

Public support

  • Provider

    Ministry of Education, Youth and Sports

  • Programme

    Health and quality of life

  • Call for proposals

    Zdravý a kvalitní život 1 (SMSM2006002B1)

  • Main participants

  • Contest type

    VS - Public tender

  • Contract ID

    1182/2010-31

Alternative language

  • Project name in Czech

    Kompletní analýza chromatinové struktury genomu pro diagnostiku a terapii rakoviny.

  • Annotation in Czech

    Genom je zabalen v buněčném jádře do nukleoproteinové struktury označované jako chromatin. Jakékoli transakce na DNA vyžadují interakci chromatinu s transkripčními, replikačními a reparačními faktory. Struktura chromatinu na úrovní celého genomu a jeho interakce s klíčovými faktory nádorové transformace solidních tumorů a leukemií budou studovány metodikami mikročipové hybridizace za účelem identifikovat mechanismy nádorové transformace.

Scientific branches

  • R&D category

    ZV - Basic research

  • CEP classification - main branch

    EB - Genetics and molecular biology

  • CEP - secondary branch

    FD - Oncology and haematology

  • CEP - another secondary branch

    ED - Physiology

  • OECD FORD - equivalent branches <br>(according to the <a href="http://www.vyzkum.cz/storage/att/E6EF7938F0E854BAE520AC119FB22E8D/Prevodnik_oboru_Frascati.pdf">converter</a>)

    10603 - Genetics and heredity (medical genetics to be 3)<br>10604 - Reproductive biology (medical aspects to be 3)<br>10605 - Developmental biology<br>10608 - Biochemistry and molecular biology<br>10609 - Biochemical research methods<br>30101 - Human genetics<br>30105 - Physiology (including cytology)<br>30204 - Oncology<br>30205 - Hematology

Completed project evaluation

  • Provider evaluation

    U - Uspěl podle zadání (s publikovanými či patentovanými výsledky atd.)

  • Project results evaluation

    The research plan has been solved in accordance with the task. A number of original results has been achieved, namely theoretical as well as the results with possibilities for a direct application

Solution timeline

  • Realization period - beginning

    Jul 1, 2006

  • Realization period - end

    Jun 30, 2011

  • Project status

    U - Finished project

  • Latest support payment

    Feb 25, 2011

Data delivery to CEP

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

  • Data delivery code

    CEP12-MSM-2B-U/01:1

  • Data delivery date

    Jul 3, 2012

Finance

  • Total approved costs

    53,217 thou. CZK

  • Public financial support

    47,631 thou. CZK

  • Other public sources

    0 thou. CZK

  • Non public and foreign sources

    5,586 thou. CZK