Integrated Micro-Nano-Opto Fluidic systems for high-content diagnosis and studies of rare cancer cells
Project goals
The project aims at developing a new integrated and automated microfluidic tool for cancer cells screening. It will involve a new generation of bio-functionalised multifunctional magnetic nano and microparticles which will be self-assembled by a Hierarchial Templated Self-Assembly mechanism into high-aspect ratio reversible arrays. Technological developments will be validated regarding the analysis of circulating tumour cells or "micrometastases" and the molecular typing of minimally invasive microsamples from tumours. The project will also yield new tools for research and drug-discovery allowing to study at the single molecule scale in single cancer cells from patients the fate and action of new generation anticancer drugs using innovative dynamic tracking of Quantum dots.
Keywords
nanoparticlesself-assemblybioNEMSbioinformaticsnano-opticscancer diagnosisdrug targeting
Public support
Provider
Ministry of Education, Youth and Sports
Programme
—
Call for proposals
FP7-NMP-2008-SMALL-2
Main participants
—
Contest type
RP - Co-financing of EC programme
Contract ID
1089/2011-321
Alternative language
Project name in Czech
Integrated Micro-Nano-Opto Fluidic systems for high-content diagnosis and studies of rare cancer cells
Annotation in Czech
The project aims at developing a new integrated and automated microfluidic tool for cancer cells screening. It will involve a new generation of bio-functionalised multifunctional magnetic nano and microparticles which will be self-assembled by a Hierarchial Templated Self-Assembly mechanism into high-aspect ratio reversible arrays. Technological developments will be validated regarding the analysis of circulating tumour cells or "micrometastases" and the molecular typing of minimally invasive microsamples from tumours. The project will also yield new tools for research and drug-discovery allowing to study at the single molecule scale in single cancer cells from patients the fate and action of new generation anticancer drugs using innovative dynamic tracking of Quantum dots.
Scientific branches
R&D category
ZV - Basic research
CEP classification - main branch
CD - Macromolecular chemistry
CEP - secondary branch
FS - Medical facilities, apparatus and equipment
CEP - another secondary branch
BO - Biophysics
10404 - Polymer science
10610 - Biophysics
20601 - Medical engineering
20602 - Medical laboratory technology (including laboratory samples analysis; diagnostic technologies) (Biomaterials to be 2.9 [physical characteristics of living material as related to medical implants, devices, sensors])
Completed project evaluation
Provider evaluation
U - Uspěl podle zadání (s publikovanými či patentovanými výsledky atd.)
Project results evaluation
Following the condition that the candidate of financial contribution was evaluated and afterwards selected by international provider in accordance with the rules of the program the Ministry of Education, Youth ans Sports does not realize the evaluation of project results. The project is evaluated only after its approval by an international provider.
Solution timeline
Realization period - beginning
Jul 1, 2009
Realization period - end
Jun 30, 2012
Project status
U - Finished project
Latest support payment
Apr 2, 2012
Data delivery to CEP
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data delivery code
CEP13-MSM-7E-U/01:1
Data delivery date
Jun 28, 2013
Finance
Total approved costs
3,059 thou. CZK
Public financial support
3,059 thou. CZK
Other public sources
0 thou. CZK
Non public and foreign sources
0 thou. CZK
Basic information
Recognised costs
3 059 CZK thou.
Public support
3 059 CZK thou.
100%
Provider
Ministry of Education, Youth and Sports
CEP
CD - Macromolecular chemistry
Solution period
01. 07. 2009 - 30. 06. 2012