Spin-based nanolytics – Turning today’s quantum technology research frontier into tomorrow’s diagnostic devices
Public support
Provider
Ministry of Education, Youth and Sports
Programme
—
Call for proposals
—
Main participants
Ústav organické chemie a biochemie AV ČR, v. v. i.
Contest type
M2 - International cooperation
Contract ID
MSMT-9964/2018-2/4
Alternative language
Project name in Czech
Spin-based nanolytics – Turning today’s quantum technology research frontier into tomorrow’s diagnostic devices
Annotation in Czech
Objective 1: NanoSpin will push the sensitivity limit of NMR spectroscopy to single molecules while maintaining a spectral resolution sufficient to resolve chemical shifts and J-couplings using the quantum interaction of the colour centre and the nuclei in the molecule (nanoscale-NMR) to enable disruptive new quantum experiments. Objective 2: NanoSpin will integrate its transformative quantum-based hyperpolarisation technology with ESR-on-a-chip, NMR-on-a-chip and lab-on-a-chip technology (HyperNMR-on-a-chip) to provide a functionality and performance greatly exceeding that of today’s benchtop spectrometers in miniaturised, portable units at sufficiently low costs to turn the field of spin-based analytics from an expert laboratory technology to a widely used in-field method with new applications in personalized medicine and home diagnostics. Objective 3: NanoSpin will integrate its transformative quantum-based hyperpolarisation technology into commercial high-end NMR spectrometers to reduce 1’000 to 10’000-fold the measurement time in standard NMR experiments to open up entirely new application scenarios for NMR including, e.g. MR-based metabolomics and MR-based drug screening for which the throughput of today’s instruments is prohibitively small. Moreover, the new possibilities associated with the greatly reduced measurement times can be used to study fundamental questions in structural biology such as protein folding near surfaces.
Scientific branches
R&D category
ZV - Basic research
OECD FORD - main branch
10401 - Organic chemistry
OECD FORD - secondary branch
10401 - Organic chemistry
OECD FORD - another secondary branch
10401 - Organic chemistry
CEP - equivalent branches <br>(according to the <a href="http://www.vyzkum.cz/storage/att/E6EF7938F0E854BAE520AC119FB22E8D/Prevodnik_oboru_Frascati.pdf">converter</a>)
CC - Organic chemistry
Completed project evaluation
Provider evaluation
V - Vynikající výsledky projektu (s mezinárodním významem atd.)
Project results evaluation
The project was focused on the use of optical defects in diamond for quantum measurements and manipulation of spin optical states. A new method for generation of NV centers was established and use of defected nanodiamonds for hyperpolarization and practical measurements was studied.
Solution timeline
Realization period - beginning
Jan 1, 2018
Realization period - end
Feb 28, 2021
Project status
U - Finished project
Latest support payment
Feb 26, 2020
Data delivery to CEP
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data delivery code
CEP22-MSM-8C-U
Data delivery date
Jun 29, 2022
Finance
Total approved costs
3,720 thou. CZK
Public financial support
3,720 thou. CZK
Other public sources
0 thou. CZK
Non public and foreign sources
0 thou. CZK