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Czech Infrastructure for Integrative Structural Biology for Human Health

Public support

  • Provider

    Ministry of Education, Youth and Sports

  • Programme

  • Call for proposals

  • Main participants

    Masarykova univerzita / Středoevropský technologický institut

  • Contest type

    OP - EU Operational Programme

  • Contract ID

    16_013/0001776_01

Alternative language

  • Project name in Czech

    Česká infrastruktura pro integrativní strukturní biologii pro lidské zdraví

  • Annotation in Czech

    Cílem projektu je podporovat nejmodernější výzkum v oblasti věd o živé přírodě v České republice prostřednictvím modernizace laboratoří CIISB a jejich využitím ve výzkumu zaměřeném na molekulární interakce ovlivňující lidské zdraví. Projekt CIISB4HEALTH má dva specifické cíle: (1) Cílem projektu je modernizace infrastruktury CIISB v souladu s potřebami tuzemských uživatelů - investiční plán každé členské laboratoře byl projednán s výzkumnými pracovníky a schválen Výborem uživatelů (User Committee). Národní orgány potřebu tohoto upgradu uznaly zahrnutím infrastruktury CIISB do národní Cestovní mapy ČR velkých infrastruktur pro výzkum, experimentální vývoj a inovace pro léta 2016 až 2022. (2) Cílem projektu je podpořit inovativní směry výzkumu v členských institucích CIISB zaměřené na interakce biomolekul relevantních pro lidské zdraví a léčbu nemocí. Projekt CIISB4HEALTH zejména rozšíří znalosti o biomolekulárních interakcích souvisejících s (i) infekčními nemocemi; (ii) patologiemi nervových a svalových buněk; (iii) vývojem a léčbou rakoviny.

Scientific branches

  • R&D category

    IF - RDI infrastructure

  • CEP classification - main branch

    EI - Biotechnology and bionics

  • CEP - secondary branch

    BO - Biophysics

  • CEP - another secondary branch

    FA - Cardiovascular diseases including cardio-surgery

  • OECD FORD - equivalent branches <br>(according to the <a href="http://www.vyzkum.cz/storage/att/E6EF7938F0E854BAE520AC119FB22E8D/Prevodnik_oboru_Frascati.pdf">converter</a>)

    10610 - Biophysics<br>20801 - Environmental biotechnology<br>20802 - Bioremediation, diagnostic biotechnologies (DNA chips and biosensing devices) in environmental management<br>20803 - Environmental biotechnology related ethics<br>20901 - Industrial biotechnology<br>20902 - Bioprocessing technologies (industrial processes relying on biological agents to drive the process) biocatalysis, fermentation<br>20903 - Bioproducts (products that are manufactured using biological material as feedstock) biomaterials, bioplastics, biofuels, bioderived bulk and fine chemicals, bio-derived novel materials<br>30201 - Cardiac and Cardiovascular systems<br>30401 - Health-related biotechnology<br>30402 - Technologies involving the manipulation of cells, tissues, organs or the whole organism (assisted reproduction)<br>30403 - Technologies involving identifying the functioning of DNA, proteins and enzymes and how they influence the onset of disease and maintenance of well-being (gene-based diagnostics and therapeutic interventions [pharmacogenomics, gene-based therapeutics])<br>30404 - Biomaterials (as related to medical implants, devices, sensors)<br>30405 - Medical biotechnology related ethics<br>40401 - Agricultural biotechnology and food biotechnology<br>40402 - GM technology (crops and livestock), livestock cloning, marker assisted selection, diagnostics (DNA chips and biosensing devices for the early/accurate detection of diseases) biomass feedstock production technologies, biopharming<br>40403 - Agricultural biotechnology related ethics

Completed project evaluation

  • Provider evaluation

    V - Vynikající výsledky projektu (s mezinárodním významem atd.)

  • Project results evaluation

    The project enabled the modernization of the Czech infrastructure for integrative structural biology and supported its use in research focused on molecular interactions that affect human health. The acquired investments were integrated into the shared laboratories of CEITEC MU and IBT and significantly supported innovative research directions focusing on the interactions of biomolecules relevant to human health and disease treatment. The availability of modern technologies has significantly increased the level of Czech biomedical research. During the implementation of the project, the number of requests for open access from external users increased significantly to 94 in 2020 compared to 50 in 2017. The project thus contributed to the development of the European INSTRUCT infrastructure and made state-of-the-art technology and instrumentation available to the Czech biomedical research community.

Solution timeline

  • Realization period - beginning

    Apr 1, 2017

  • Realization period - end

    Mar 31, 2021

  • Project status

    U - Finished project

  • Latest support payment

    Dec 17, 2020

Data delivery to CEP

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

  • Data delivery code

    CEP22-MSM-EF-U

  • Data delivery date

    Jun 30, 2022

Finance

  • Total approved costs

    276,381 thou. CZK

  • Public financial support

    276,381 thou. CZK

  • Other public sources

    0 thou. CZK

  • Non public and foreign sources

    13,934 thou. CZK