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*Modulators of skin barrier properties and their use in drugs formulation.

Project goals

*Research and development oriented towards new modulators of the skin barrier properties and preparations for dermal and transdermal delivery of active substances in pharmacy or cosmetics. Elaboration of data for introduction of new products, evaluationof their properties and a proposal of applications.

Keywords

modulators of skin barrier propertiesenhancerstransdermal applicationscarbamic acidstranskarbam

Public support

  • Provider

    Ministry of Industry and Trade

  • Programme

    TANDEM

  • Call for proposals

    TANDEM 2 (SMPO200500008)

  • Main participants

    —

  • Contest type

    VS - Public tender

  • Contract ID

    FT-TA2/012

Alternative language

  • Project name in Czech

    *Modulátory bariérových vlastností kůže a jejich využití při tvorbě léčiv.

  • Annotation in Czech

    *Výzkum a vývoj orientovaný na nové modulátory bariérových vlastností kůže a aplikačních systémů pro transdermální aplikaci aktivních látek ve farmacii nebo kosmetice. Vypracování podkladů pro zavádění nových výrobků, testování vlastností a zpracování návrhu aplikací.

Scientific branches

  • R&D category

    PV - Industrial research

  • CEP classification - main branch

    FR - Pharmacology and apothecary chemistry

  • CEP - secondary branch

    FO - Dermatology and venereology

  • CEP - another secondary branch

    —

  • 30104 - Pharmacology and pharmacy
    30216 - Dermatology and venereal diseases

Completed project evaluation

  • Provider evaluation

    U - Uspěl podle zadání (s publikovanými či patentovanými výsledky atd.)

  • Project results evaluation

    Several batches of the new modulator of skin barrier properties transkarbam 12 (T12) were produced. The pharmaco-toxicology data of it were determined. Analytical methods for its evaluation were worked up.

Solution timeline

  • Realization period - beginning

    Jan 11, 2005

  • Realization period - end

    Dec 31, 2007

  • Project status

    U - Finished project

  • Latest support payment

    Mar 30, 2007

Data delivery to CEP

  • Confidentiality

    C - Předmět řešení projektu podléhá obchodnímu tajemství (§ 504 Občanského zákoníku), ale název projektu, cíle projektu a u ukončeného nebo zastaveného projektu zhodnocení výsledku řešení projektu (údaje P03, P04, P15, P19, P29, PN8) dodané do CEP, jsou upraveny tak, aby byly zveřejnitelné.

  • Data delivery code

    CEP08-MPO-FT-U/01:1

  • Data delivery date

    Jun 20, 2008

Finance

  • Total approved costs

    22,129 thou. CZK

  • Public financial support

    9,950 thou. CZK

  • Other public sources

    0 thou. CZK

  • Non public and foreign sources

    12,180 thou. CZK

Recognised costs

22 129 CZK thou.

Public support

9 950 CZK thou.

0%

Provider

Ministry of Industry and Trade

CEP

FR - Pharmacology and apothecary chemistry

Solution period

11. 01. 2005 - 31. 12. 2007

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