Construction and large-scale production of recombinant proteins, derived from Epstaein-Barr virus nuclear antigen 1 (EBNA 1), and their application to the diagnostics of infectious diseasea.
Public support
Provider
Ministry of Industry and Trade
Programme
TANDEM
Call for proposals
TANDEM 2 (SMPO200500008)
Main participants
—
Contest type
VS - Public tender
Contract ID
FT-TA2/015
Alternative language
Project name in Czech
Vývoj a příprava rekombinantních proteinů odvozených z antigenní struktury proteinu EBNA1 viru Epsteina a Barrové a jejich využití pro diagnostiku infekčních onemocnění.
Annotation in Czech
Cílem projektu je vyvinout a diagnosticky ověřit rekombinantní proteiny, obsahující pouze virově specifické antigenní determinanty EBNA 1, a s jejich pomocí zkonstruovat diagnostickou soupravu na stanovení lidských protilátek proti tomuto proteinu.
Scientific branches
R&D category
VV - Exeperimental development
CEP classification - main branch
FN - Epidemiology, infection diseases and clinical immunology
CEP - secondary branch
EB - Genetics and molecular biology
CEP - another secondary branch
—
OECD FORD - equivalent branches <br>(according to the <a href="http://www.vyzkum.cz/storage/att/E6EF7938F0E854BAE520AC119FB22E8D/Prevodnik_oboru_Frascati.pdf">converter</a>)
10603 - Genetics and heredity (medical genetics to be 3)<br>10604 - Reproductive biology (medical aspects to be 3)<br>10605 - Developmental biology<br>10608 - Biochemistry and molecular biology<br>10609 - Biochemical research methods<br>30101 - Human genetics<br>30302 - Epidemiology<br>30303 - Infectious Diseases
Completed project evaluation
Provider evaluation
U - Uspěl podle zadání (s publikovanými či patentovanými výsledky atd.)
Project results evaluation
The recombinant EBNA-1 antigens were prepared and technology of their production, isolation and purification was developed. The high sensitive diagnostic ELISA kit with better diagnostic availability was prepared.
Solution timeline
Realization period - beginning
Aug 1, 2005
Realization period - end
Jul 31, 2007
Project status
U - Finished project
Latest support payment
Mar 23, 2007
Data delivery to CEP
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data delivery code
CEP08-MPO-FT-U/01:1
Data delivery date
Jun 20, 2008
Finance
Total approved costs
4,344 thou. CZK
Public financial support
1,616 thou. CZK
Other public sources
0 thou. CZK
Non public and foreign sources
2,727 thou. CZK