Discovery libraries of chemical compounds.
Project goals
A new laboratory of combinatorial chemistry will be established in ICT Prague. A team of scientists in cooperation of ICT Prague and RE&D VÚFB, Ltd. will be working on new methods of parallel syntheses and dynamic combinatorial libraries. The results will be used for production of discovery combinatorial libraries - collection of highly diverse compounds for screening for biological activities.
Keywords
combinatorial chemistrycombinatorial librariesdiscovery librariessolid phase synthesis
Public support
Provider
Ministry of Industry and Trade
Programme
TANDEM
Call for proposals
TANDEM 2 (SMPO200500008)
Main participants
—
Contest type
VS - Public tender
Contract ID
FT-TA2/054
Alternative language
Project name in Czech
Discovery knihovny chemických látek.
Annotation in Czech
Vznik na VŠCHT laboratoře kombinatorní chemie, kde se budou společně s firmou RE&D VÚFB, s.r.o. vypracovávat metody paralelních syntéz a studovat dynamické kombinatorní systémy. Výsledky výzkumu se budou realizovat v podobě výroby kombinatoriálních discovery knihoven - mnoha různých diverzních látek pro testování.
Scientific branches
Completed project evaluation
Provider evaluation
U - Uspěl podle zadání (s publikovanými či patentovanými výsledky atd.)
Project results evaluation
Technology of combinatorial synthesis was developed on the example of oxazolidinones, pharmacologically interesting compounds. Research partner ICTP developed another suitable synthesis of compound libraries.
Solution timeline
Realization period - beginning
Jan 1, 2005
Realization period - end
Dec 31, 2008
Project status
U - Finished project
Latest support payment
Apr 29, 2008
Data delivery to CEP
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data delivery code
CEP09-MPO-FT-U/02:2
Data delivery date
Apr 14, 2010
Finance
Total approved costs
10,633 thou. CZK
Public financial support
6,525 thou. CZK
Other public sources
0 thou. CZK
Non public and foreign sources
4,109 thou. CZK
Basic information
Recognised costs
10 633 CZK thou.
Public support
6 525 CZK thou.
61%
Provider
Ministry of Industry and Trade
CEP
CC - Organic chemistry
Solution period
01. 01. 2005 - 31. 12. 2008