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Influence of physiological processes on reliability and temporal fluctuations of human brain connectivity measured by fMRI

Project goals

There has been emerging development of methods for studying connectivity in human brain. However, the results of these methods are strongly influenced by non-neural components of signal, particularly by physiological processes, e.g. heart beating and breathing. The project is aimed on studying the ways in which the physiological processes affect the connectivity results. In this project, we treat the physiological processes either as a noise component or as a cause of temporal fluctuations of connectivity.

Keywords

physiological noiseconnectivityfMRItemporal fluctuationsresting-state networksfunctional connectivitynoise reduction

Public support

  • Provider

    Czech Science Foundation

  • Programme

    Standard projects

  • Call for proposals

    Standardní projekty 18 (SGA0201400001)

  • Main participants

    Masarykova univerzita / Středoevropský technologický institut

  • Contest type

    VS - Public tender

  • Contract ID

    14-33143S

Alternative language

  • Project name in Czech

    Vliv fyziologických procesů na reliabilitu a časovou proměnlivost konektivity v lidském mozku měřené pomocí fMRI

  • Annotation in Czech

    Studium konektivity lidského mozku je oblast ve které dochází k rychlému rozvoji metod. Avšak výsledky těchto metod jsou silně ovlivněny sožkami signálu, které nemají neurální původ, zejména fyziologickými procesy jako je srdeční činnost a dýchání. Cílem projektu je studium projevů fyziologických procesů ve vztahu k ovlivnění výsledků konektivity. V projektu se zabýváme fyziologickými procesy ze dvou pohledů - jako šumovou složkou a jako příčinou časové fluktuace konektivity.

Scientific branches

  • R&D category

    ZV - Basic research

  • CEP classification - main branch

    FH - Neurology, neuro-surgery, nuero-sciences

  • CEP - secondary branch

    JD - Use of computers, robotics and its application

  • CEP - another secondary branch

    BD - Information theory

  • 10102 - Applied mathematics
    10201 - Computer sciences, information science, bioinformathics (hardware development to be 2.2, social aspect to be 5.8)
    20204 - Robotics and automatic control
    20205 - Automation and control systems
    30103 - Neurosciences (including psychophysiology)
    30210 - Clinical neurology

Completed project evaluation

  • Provider evaluation

    U - Uspěl podle zadání (s publikovanými či patentovanými výsledky atd.)

  • Project results evaluation

    The main contribution of this project is in the area of neuroscience reserch, neuroimaging methods and biologic signals processing (especially the physiological noise impact to effective connectivity methods). The obtained results were published in articles and presented at conferences, these newest results will appear in journals as this project resultsevidence later.

Solution timeline

  • Realization period - beginning

    Jan 1, 2014

  • Realization period - end

    Dec 31, 2016

  • Project status

    U - Finished project

  • Latest support payment

    Apr 5, 2016

Data delivery to CEP

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

  • Data delivery code

    CEP17-GA0-GA-U/03:1

  • Data delivery date

    Jun 28, 2017

Finance

  • Total approved costs

    4,230 thou. CZK

  • Public financial support

    4,230 thou. CZK

  • Other public sources

    0 thou. CZK

  • Non public and foreign sources

    0 thou. CZK

Recognised costs

4 230 CZK thou.

Public support

4 230 CZK thou.

0%


Provider

Czech Science Foundation

CEP

FH - Neurology, neuro-surgery, nuero-sciences

Solution period

01. 01. 2014 - 31. 12. 2016