Mechanisms underlying modulation of immune cell functions by cAMP
Public support
Provider
Czech Science Foundation
Programme
Standard projects
Call for proposals
Standardní projekty 11 (SGA02008GA-ST)
Main participants
—
Contest type
VS - Public tender
Contract ID
310-08-0447
Alternative language
Project name in Czech
Mechanismy jimiž cAMP moduluje funkce buněk imunitního systému
Annotation in Czech
Cílem tohoto projektu je identifikovat signální dráhy, jimiž cAMP moduluje buněčné funkce imunitního systému a potlačuje tak antibakteriální imunitu. Nedávno jsme pozorovali, že zvýšení cytosolické hladiny cAMP vede u fagocytů k rychlé dezorganizaci aktin
Scientific branches
R&D category
ZV - Basic research
CEP classification - main branch
EC - Immunology
CEP - secondary branch
CE - Biochemistry
CEP - another secondary branch
EE - Microbiology, virology
OECD FORD - equivalent branches <br>(according to the <a href="http://www.vyzkum.cz/storage/att/E6EF7938F0E854BAE520AC119FB22E8D/Prevodnik_oboru_Frascati.pdf">converter</a>)
10606 - Microbiology<br>10607 - Virology<br>10608 - Biochemistry and molecular biology<br>10609 - Biochemical research methods<br>30102 - Immunology
Completed project evaluation
Provider evaluation
V - Vynikající výsledky projektu (s mezinárodním významem atd.)
Project results evaluation
Molecular mechanisms paralyzing the function of dendritic cells and phagocytes in course of Bordetella pertussis infection were clarified. Planed aims were completed, results were presented in 12 papers published in journals with IF and 1 patent. Excellent realization of grant project.
Solution timeline
Realization period - beginning
Jan 1, 2008
Realization period - end
Dec 31, 2012
Project status
U - Finished project
Latest support payment
Apr 1, 2012
Data delivery to CEP
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data delivery code
CEP13-GA0-GA-U/02:3
Data delivery date
May 17, 2016
Finance
Total approved costs
10,247 thou. CZK
Public financial support
10,247 thou. CZK
Other public sources
0 thou. CZK
Non public and foreign sources
0 thou. CZK