Investigation of algae and cyanobacteria as producers of biologically active substances
Project goals
There is increasing evidence from the literature that at least some algae are able to produce plant growth regulators and antimicrobial compounds. Both groups of compounds can be considered as "valuable products" for the agriculture and medicine. Withrespect to this we propose: (1) to collect new strains, optimise their growth in microtiter plates and characterise their growth parameters, (2) to develop simple screening system for analyses of phytohormone production of different algae clones andstrains,(3) to characterise precisely endogenous levels of different plant hormone metabolites by very sophisticated techniques, (4) to isolate and identify new algae growth regulators, and (5) to test biological activities of algal extracts indifferent assay (cytotoxicity, PGR bioassays, antiviral and antimicrobial activities). We hope that this project will finally led to selection of algal clones and strains overproducing plant hormones which could be useful for different agricultural
Keywords
Public support
Provider
Czech Science Foundation
Programme
Standard projects
Call for proposals
Standardní projekty 2 (SGA02003GA-ST)
Main participants
Univerzita Palackého v Olomouci / Přírodovědecká fakulta
Contest type
VS - Public tender
Contract ID
—
Alternative language
Project name in Czech
Studium produkce biologicky aktivních látek řasami a sinicemi
Annotation in Czech
V posledních letech se v literatuře stále častěji objevují zmínky o tom, že mnohé řasy mohou produkovat růstové regulátory a antibakteriální látky. Možnosti využití obou skupin látek lze očekávat jak v zemědělství, tak v medicíně. Vzhledem k těmtoskutečnostem je třeba 1) vybrat vhodné kmeny, optimalizovat jejich kultivaci v sérologických destičkách a charakterizovat jejich růstové parametry, 2) vyvinout jednoduché metody testování produkce fytohormonů různými kmeny řas, 3) exaktními metodamistanovit hladiny různých rostlinných hormonů v řasách, 4) izolovat a identifikovat nové řasové růstové regulátory a 5) testovat biologické aktivity řasových extraktů. Věříme, že tento projekt povede k výběru řasových kmenů, produkujících rostlinnéhormony, které mohou být použitelné v zemědělství. Chceme se pokusit izolovat řasy, které produkují obtížně syntetizovatelné fytohormony. Takové řasy by mohly být využity na jejich výrobu.
Scientific branches
R&D category
ZV - Basic research
CEP classification - main branch
EF - Botany
CEP - secondary branch
ED - Physiology
CEP - another secondary branch
EI - Biotechnology and bionics
10611 - Plant sciences, botany
10612 - Mycology
20801 - Environmental biotechnology
20802 - Bioremediation, diagnostic biotechnologies (DNA chips and biosensing devices) in environmental management
20803 - Environmental biotechnology related ethics
20901 - Industrial biotechnology
20902 - Bioprocessing technologies (industrial processes relying on biological agents to drive the process) biocatalysis, fermentation
20903 - Bioproducts (products that are manufactured using biological material as feedstock) biomaterials, bioplastics, biofuels, bioderived bulk and fine chemicals, bio-derived novel materials
30105 - Physiology (including cytology)
30401 - Health-related biotechnology
30402 - Technologies involving the manipulation of cells, tissues, organs or the whole organism (assisted reproduction)
30403 - Technologies involving identifying the functioning of DNA, proteins and enzymes and how they influence the onset of disease and maintenance of well-being (gene-based diagnostics and therapeutic interventions [pharmacogenomics, gene-based therapeutics])
30404 - Biomaterials (as related to medical implants, devices, sensors)
30405 - Medical biotechnology related ethics
40401 - Agricultural biotechnology and food biotechnology
40402 - GM technology (crops and livestock), livestock cloning, marker assisted selection, diagnostics (DNA chips and biosensing devices for the early/accurate detection of diseases) biomass feedstock production technologies, biopharming
40403 - Agricultural biotechnology related ethics
Completed project evaluation
Provider evaluation
V - Vynikající výsledky projektu (s mezinárodním významem atd.)
Project results evaluation
Simple method of algal strain cultivation in microtiter plates were optimised on 30 green algae and 10 cyanobacteria strains. Screening system for analyses of phytohormone overproduction of different algal clones and strains and the method of isolation,
Solution timeline
Realization period - beginning
Jan 1, 2003
Realization period - end
Jan 1, 2005
Project status
U - Finished project
Latest support payment
—
Data delivery to CEP
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data delivery code
CEP06-GA0-GA-U/07:6
Data delivery date
Jan 15, 2009
Finance
Total approved costs
5,556 thou. CZK
Public financial support
1,140 thou. CZK
Other public sources
4,416 thou. CZK
Non public and foreign sources
0 thou. CZK
Basic information
Recognised costs
5 556 CZK thou.
Public support
1 140 CZK thou.
20%
Provider
Czech Science Foundation
CEP
EF - Botany
Solution period
01. 01. 2003 - 01. 01. 2005