Metal-fullerene nanocomposites and their biological applications
Project goals
The main topic of the grant project is thestudy of thin films of hybrid composites based on carbon allotropes (especiallyC60) and transition (and noble) metals, their preparation, modification andcharacterization, and also the study of their biological properties (i.e.,biotolerance, adhesion of bone-type cells, their growth, differentiation,etc.). The purpose is to develop novel hybrid materials with well-definedstructures and interesting properties attractive for applications (e.g., fortissue engineering). For fabrication of the composites, suitable depositiontechniques will be used; for characterization of the films an arsenal ofanalytical methods will be at our disposal. The preliminary experimentsdemonstrated an interesting aspect of the project ?the possibility ofpreparing composite materials with regular structures at a (sub-) micron scalelevel either created due to spontaneous self-organization (induced by a certaindeposition kinetics), or because of coordinated phase separation initiated bythermal annealing or irradiation with energy ion beams. The specific goal ofthis project is to shed more light on the onset, mechanisms and kinetics of theabove-mentioned phenomena.
Keywords
Public support
Provider
Czech Science Foundation
Programme
Standard projects
Call for proposals
Standardní projekty 14 (SGA02011GA-ST)
Main participants
—
Contest type
VS - Public tender
Contract ID
P107-11-1856
Alternative language
Project name in Czech
Nanokompozity kov-fulleren a jejich biologické aplikace
Annotation in Czech
Předmětem grantového projektu je studiumtenkých vrstev hybridních kompozitů na bázi allotropů uhlíku (zejména fullerenůC60) a tranzitivních (a vzácných) kovů, jejich příprava, modifikace acharakterizace a studium jejich biologických vlastností (tj. biotolerance,adheze kostních buněk, jejich růst, diferenciace apod.). Účelem je vytvořitnové hybridní materiály s dobře definovanou strukturou a zajímavýmivlastnostmi, perspektivními pro cílené aplikace (např. v tkáňovém inženýrství).Pro přípravu kompozitů budou využity vhodné metodiky s řízenou depozičníkinetikou; pro fyzikální charakterizaci vrstev bude k dispozici široké spektrumanalytických metod. V předběžných experimentech byl demonstrován zajímavýaspekt předkládaného projektu - možnost připravit kompozity s pravidelnou(sub-)mikronovou strukturou vytvořenou buď spontánní samoorganizací (při vhodnédepoziční kinetice) nebo koordinovaným fázovým rozdělením při termálním žíháníresp. ozařování energetickými iontovými svazky. Specifickým cílem projektu jeobjasnění vzniku, mechanismu a kinetiky těchto jevů.
Scientific branches
R&D category
ZV - Basic research
CEP classification - main branch
JI - Composite materials
CEP - secondary branch
EI - Biotechnology and bionics
CEP - another secondary branch
—
20505 - Composites (including laminates, reinforced plastics, cermets, combined natural and synthetic fibre fabrics; filled composites)
20801 - Environmental biotechnology
20802 - Bioremediation, diagnostic biotechnologies (DNA chips and biosensing devices) in environmental management
20803 - Environmental biotechnology related ethics
20901 - Industrial biotechnology
20902 - Bioprocessing technologies (industrial processes relying on biological agents to drive the process) biocatalysis, fermentation
20903 - Bioproducts (products that are manufactured using biological material as feedstock) biomaterials, bioplastics, biofuels, bioderived bulk and fine chemicals, bio-derived novel materials
30401 - Health-related biotechnology
30402 - Technologies involving the manipulation of cells, tissues, organs or the whole organism (assisted reproduction)
30403 - Technologies involving identifying the functioning of DNA, proteins and enzymes and how they influence the onset of disease and maintenance of well-being (gene-based diagnostics and therapeutic interventions [pharmacogenomics, gene-based therapeutics])
30404 - Biomaterials (as related to medical implants, devices, sensors)
30405 - Medical biotechnology related ethics
40401 - Agricultural biotechnology and food biotechnology
40402 - GM technology (crops and livestock), livestock cloning, marker assisted selection, diagnostics (DNA chips and biosensing devices for the early/accurate detection of diseases) biomass feedstock production technologies, biopharming
40403 - Agricultural biotechnology related ethics
Completed project evaluation
Provider evaluation
U - Uspěl podle zadání (s publikovanými či patentovanými výsledky atd.)
Project results evaluation
The main contribution of the project can be seen in a development of new hybrid materials systems based on metal ? fullerene C60 and in an evaluation of these systems from the viewpoint of biocompatibility. The results have shown a positive response of bone cells and indicated a possible use of such hybrid layers in medicine. However, the results have not been adequately published yet.
Solution timeline
Realization period - beginning
Jan 1, 2011
Realization period - end
Dec 31, 2013
Project status
U - Finished project
Latest support payment
Jun 6, 2013
Data delivery to CEP
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data delivery code
CEP14-GA0-GA-U/01:1
Data delivery date
Jul 1, 2014
Finance
Total approved costs
5,812 thou. CZK
Public financial support
5,812 thou. CZK
Other public sources
0 thou. CZK
Non public and foreign sources
0 thou. CZK
Basic information
Recognised costs
5 812 CZK thou.
Public support
5 812 CZK thou.
100%
Provider
Czech Science Foundation
CEP
JI - Composite materials
Solution period
01. 01. 2011 - 31. 12. 2013