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Carbon nanolayers, nanostructures and nanoparticles on substrates for potential application in medicine and electronics

Project goals

Main aims of the project are: (i) To create and study novel carbon structures on polymer substrates, applicable for construction of bioartificial replacements of damaged tissues and organs, for creation of cell microarrays, and also in electronics. These layers will be deposited by sputtering, evaporation and chemical vapor deposition (CVD) method; (ii) Grafting carbon nanoparticles on substrates pre-activated by plasma irradiation. The carbon nanoparticles are known to have super adsorption properties which will be utilized for their adsorption onto modified polymer substrate grafted by suitable molecules. Further the carbon nanoparticles will be grafted directly onto foils or nanofibres via chemical bonds. For this purpose the nanoparticles will be preliminarily functionalized by groups which are able to interact with plasma activate polymer surface. These samples will be tested as substrates for cells proliferation and their usage in tissue engineering. Also these structures are attractive for electronics.

Keywords

carbonnanolayernanoparticlemedicineelectronics

Public support

  • Provider

    Czech Science Foundation

  • Programme

    Standard projects

  • Call for proposals

    Standardní projekty 15 (SGA02012GA-ST)

  • Main participants

    Fyziologický ústav AV ČR, v. v. i.
    Vysoká škola chemicko-technologická v Praze / Fakulta chemické technologie

  • Contest type

    VS - Public tender

  • Contract ID

    P108-12-1168

Alternative language

  • Project name in Czech

    Uhlíkové nanovrstvy, nanostruktury a nanočástice na substrátech pro potenciální aplikace v medicíně a elektronice

  • Annotation in Czech

    V projektu budou studovány vlastnosti uhlíkových nanovrstev a nanostruktur přípravených různými depozičními technikami. Pozornost bude věnována především: (i) jejich interakci s buňkami pro potenciální využití ve tkáňovém inženýrství a (ii) elektrické, povrchové a mechanické vlastnosti (pro elektroniku). V další fázi bude studována možnost naroubovat na povrch aktivovaného polymerního substrátu uhlíkové nanostruktury, které mají superadsorpční vlastnosti. Tyto struktury budou předem chemicky funkcionalizovány. Lze předpokládat, že chemicky navázaná částice zvýší adhezi posléze deponované uhlíkové vrstvy na substrátu. I u takto naroubovaných nanostruktur na substrát bude studována jejich interakce s buňkami. Tyto materiály budou testovány jako substráty pro pěstování např. kožních buněk nebo buněk hladkého svalstva (tkáňové inženýrství). Struktura vodič/izolant (uhlíková struktura/polymer) je velmi atraktivní pro elektroniku.

Scientific branches

  • R&D category

    ZV - Basic research

  • CEP classification - main branch

    JJ - Other materials

  • CEP - secondary branch

  • CEP - another secondary branch

  • 20502 - Paper and wood
    20503 - Textiles; including synthetic dyes, colours, fibres (nanoscale materials to be 2.10; biomaterials to be 2.9)
    21001 - Nano-materials (production and properties)
    21002 - Nano-processes (applications on nano-scale); (biomaterials to be 2.9)

Completed project evaluation

  • Provider evaluation

    U - Uspěl podle zadání (s publikovanými či patentovanými výsledky atd.)

  • Project results evaluation

    New information on adhesiveness, proliferation and differentiation of cells on new prepared bioactive artificial materials were gained. In field of tissue ingeneering these materials can play an important role as scaffolds for skin cells growth. The obtained results are well described in the final report. The results were published in respected journals. Many students were involved in the project.

Solution timeline

  • Realization period - beginning

    Jan 1, 2012

  • Realization period - end

    Dec 31, 2016

  • Project status

    U - Finished project

  • Latest support payment

    Apr 14, 2016

Data delivery to CEP

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

  • Data delivery code

    CEP17-GA0-GA-U/03:1

  • Data delivery date

    Jun 28, 2017

Finance

  • Total approved costs

    16,690 thou. CZK

  • Public financial support

    16,690 thou. CZK

  • Other public sources

    0 thou. CZK

  • Non public and foreign sources

    0 thou. CZK

Recognised costs

16 690 CZK thou.

Public support

16 690 CZK thou.

0%


Provider

Czech Science Foundation

CEP

JJ - Other materials

Solution period

01. 01. 2012 - 31. 12. 2016