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Chracterisation of NADPH oxidase from tobacco pollen and its role in regulation of polar cell expansion

Project goals

NADPH oxidases (NOX) activities play important roles in plant response to stress and were described as important for plant development, notably for the tip growth of Arabidopsis root hairs. We have recently described the importance of NOX for the growthof tobacco pollen tubes. However, the detailed mechanisms of NOX regulation and the role of NOX-derived reactive oxygen species (ROS) in cellular morphogenesis remain largerly unknown. In this project I intend to characterise further NOX signalling in tobacco pollen and study the regulation of this protein. By combining biochemical, microscopical and molecular biological approaches, this project will describe regulation of pollen NOX by phospholipid second messengers, calcium ions and small GTPases fromRop family. I will study intracellular localisation and dynamics of pollen NOX and search for novel interactors of the NOX protein. Pollen tubes and whole tobacco plants with altered expression of pollen NOX genes will also be studied. Obtained findingswill help to understand the knowledge of mechanism of pollination, that is crucial for hybrid plant production in agronomy.

Keywords

NADPH oxidasareaktivní formy kyslíkuRop GTPasyfosfolipidybuněčná polaritapylová láčka

Public support

  • Provider

    Czech Science Foundation

  • Programme

    Post-graduate (doctorate) grants

  • Call for proposals

    Postdoktorandské granty 9 (SGA02009GA1PD)

  • Main participants

  • Contest type

    VS - Public tender

  • Contract ID

    522/09/P299

Alternative language

  • Project name in Czech

    Charakterizace NADPH oxidasy v pylu tabáku a její úloha v regulaci polárního růstu

  • Annotation in Czech

    Během projektu budu studovat roli NADPH oxidasy a reaktivních forem kyslíku v procesu morfogeneze rostlinných buněk. NADPH oxidasa z pylu tabáku bude molekulárně charakterizována, bude studována její buněčná lokalizace a regulace vápníkem, signálními fosfolipidy a malými GTPasami.

Scientific branches

  • R&D category

    ZV - Basic research

  • CEP classification - main branch

    EB - Genetics and molecular biology

  • CEP - secondary branch

    EA - Morphology and cytology

  • CEP - another secondary branch

  • 10601 - Cell biology
    10602 - Biology (theoretical, mathematical, thermal, cryobiology, biological rhythm), Evolutionary biology
    10603 - Genetics and heredity (medical genetics to be 3)
    10604 - Reproductive biology (medical aspects to be 3)
    10605 - Developmental biology
    10608 - Biochemistry and molecular biology
    10609 - Biochemical research methods
    30101 - Human genetics

Completed project evaluation

  • Provider evaluation

    V - Vynikající výsledky projektu (s mezinárodním významem atd.)

  • Project results evaluation

    The project was excellent, both in terms of expertise and in terms of disbursement of funds.

Solution timeline

  • Realization period - beginning

    Jan 1, 2009

  • Realization period - end

    Dec 31, 2011

  • Project status

    U - Finished project

  • Latest support payment

    Apr 16, 2011

Data delivery to CEP

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

  • Data delivery code

    CEP12-GA0-GP-U/03:3

  • Data delivery date

    May 2, 2016

Finance

  • Total approved costs

    983 thou. CZK

  • Public financial support

    983 thou. CZK

  • Other public sources

    0 thou. CZK

  • Non public and foreign sources

    0 thou. CZK