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LH12116

Screening of biomarkers using micro/nanoarrays for diagnostics of neurodegenerative diseases

Public support

  • Provider

    Ministry of Education, Youth and Sports

  • Programme

    KONTAKT II

  • Call for proposals

    KONTAKT II 2 (SMSM2012LH2)

  • Main participants

    ESSENCE LINE, s.r.o.

  • Contest type

    VS - Public tender

  • Contract ID

    MSMT-6805/2013-311

Alternative language

  • Project name in Czech

    Screening biomarkerů pomocí mikro/nanočipů pro diagnózu neurodegenerativních nemocí

  • Annotation in Czech

    Cílem tohoto projektu je získat nové soubory biomarkerů ukotvených na microarrays, které budou sestaveny tak, aby poskytly nové poznatky měřením hladin těchto biomarkerů v klinických vzorcích nebo vzorcích animálních modelů. Prioritou je získat takové poznatky, které by připěly k nové diagnostice, případně k terapii těchto chorob.

Scientific branches

  • R&D category

    ZV - Basic research

  • CEP classification - main branch

    CB - Analytical chemistry, separation

  • CEP - secondary branch

    EI - Biotechnology and bionics

  • CEP - another secondary branch

    FH - Neurology, neuro-surgery, nuero-sciences

  • OECD FORD - equivalent branches <br>(according to the <a href="http://www.vyzkum.cz/storage/att/E6EF7938F0E854BAE520AC119FB22E8D/Prevodnik_oboru_Frascati.pdf">converter</a>)

    10406 - Analytical chemistry<br>20801 - Environmental biotechnology<br>20802 - Bioremediation, diagnostic biotechnologies (DNA chips and biosensing devices) in environmental management<br>20803 - Environmental biotechnology related ethics<br>20901 - Industrial biotechnology<br>20902 - Bioprocessing technologies (industrial processes relying on biological agents to drive the process) biocatalysis, fermentation<br>20903 - Bioproducts (products that are manufactured using biological material as feedstock) biomaterials, bioplastics, biofuels, bioderived bulk and fine chemicals, bio-derived novel materials<br>30103 - Neurosciences (including psychophysiology)<br>30210 - Clinical neurology<br>30401 - Health-related biotechnology<br>30402 - Technologies involving the manipulation of cells, tissues, organs or the whole organism (assisted reproduction)<br>30403 - Technologies involving identifying the functioning of DNA, proteins and enzymes and how they influence the onset of disease and maintenance of well-being (gene-based diagnostics and therapeutic interventions [pharmacogenomics, gene-based therapeutics])<br>30404 - Biomaterials (as related to medical implants, devices, sensors)<br>30405 - Medical biotechnology related ethics<br>40401 - Agricultural biotechnology and food biotechnology<br>40402 - GM technology (crops and livestock), livestock cloning, marker assisted selection, diagnostics (DNA chips and biosensing devices for the early/accurate detection of diseases) biomass feedstock production technologies, biopharming<br>40403 - Agricultural biotechnology related ethics

Completed project evaluation

  • Provider evaluation

    U - Uspěl podle zadání (s publikovanými či patentovanými výsledky atd.)

  • Project results evaluation

    In 2015, newly designed matrices and modified contemporary bioinformatic methods were applied to measuring marker levels in selected studies of neurodegenerative processes. The results have been published in expert media.

Solution timeline

  • Realization period - beginning

    Mar 1, 2012

  • Realization period - end

    Dec 31, 2015

  • Project status

    U - Finished project

  • Latest support payment

    Feb 27, 2015

Data delivery to CEP

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

  • Data delivery code

    CEP16-MSM-LH-U/01:1

  • Data delivery date

    Oct 9, 2017

Finance

  • Total approved costs

    2,992 thou. CZK

  • Public financial support

    2,142 thou. CZK

  • Other public sources

    0 thou. CZK

  • Non public and foreign sources

    850 thou. CZK