Screening of biomarkers using micro/nanoarrays for diagnostics of neurodegenerative diseases
Project goals
The aim of this project is to obtain new sets of biomarkers anchored on the microarrays that are designed to provide new knowledge by measuring the levels of these biomarkers in clinical samples or samples of animal models. The priority is to obtain suchknowledge that would contribute tom a new diagnosis or the treatment of these diseases.
Keywords
Public support
Provider
Ministry of Education, Youth and Sports
Programme
KONTAKT II
Call for proposals
KONTAKT II 2 (SMSM2012LH2)
Main participants
ESSENCE LINE, s.r.o.
Contest type
VS - Public tender
Contract ID
MSMT-6805/2013-311
Alternative language
Project name in Czech
Screening biomarkerů pomocí mikro/nanočipů pro diagnózu neurodegenerativních nemocí
Annotation in Czech
Cílem tohoto projektu je získat nové soubory biomarkerů ukotvených na microarrays, které budou sestaveny tak, aby poskytly nové poznatky měřením hladin těchto biomarkerů v klinických vzorcích nebo vzorcích animálních modelů. Prioritou je získat takové poznatky, které by připěly k nové diagnostice, případně k terapii těchto chorob.
Scientific branches
R&D category
ZV - Basic research
CEP classification - main branch
CB - Analytical chemistry, separation
CEP - secondary branch
EI - Biotechnology and bionics
CEP - another secondary branch
FH - Neurology, neuro-surgery, nuero-sciences
10406 - Analytical chemistry
20801 - Environmental biotechnology
20802 - Bioremediation, diagnostic biotechnologies (DNA chips and biosensing devices) in environmental management
20803 - Environmental biotechnology related ethics
20901 - Industrial biotechnology
20902 - Bioprocessing technologies (industrial processes relying on biological agents to drive the process) biocatalysis, fermentation
20903 - Bioproducts (products that are manufactured using biological material as feedstock) biomaterials, bioplastics, biofuels, bioderived bulk and fine chemicals, bio-derived novel materials
30103 - Neurosciences (including psychophysiology)
30210 - Clinical neurology
30401 - Health-related biotechnology
30402 - Technologies involving the manipulation of cells, tissues, organs or the whole organism (assisted reproduction)
30403 - Technologies involving identifying the functioning of DNA, proteins and enzymes and how they influence the onset of disease and maintenance of well-being (gene-based diagnostics and therapeutic interventions [pharmacogenomics, gene-based therapeutics])
30404 - Biomaterials (as related to medical implants, devices, sensors)
30405 - Medical biotechnology related ethics
40401 - Agricultural biotechnology and food biotechnology
40402 - GM technology (crops and livestock), livestock cloning, marker assisted selection, diagnostics (DNA chips and biosensing devices for the early/accurate detection of diseases) biomass feedstock production technologies, biopharming
40403 - Agricultural biotechnology related ethics
Completed project evaluation
Provider evaluation
U - Uspěl podle zadání (s publikovanými či patentovanými výsledky atd.)
Project results evaluation
In 2015, newly designed matrices and modified contemporary bioinformatic methods were applied to measuring marker levels in selected studies of neurodegenerative processes. The results have been published in expert media.
Solution timeline
Realization period - beginning
Mar 1, 2012
Realization period - end
Dec 31, 2015
Project status
U - Finished project
Latest support payment
Feb 27, 2015
Data delivery to CEP
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data delivery code
CEP16-MSM-LH-U/01:1
Data delivery date
Oct 9, 2017
Finance
Total approved costs
2,992 thou. CZK
Public financial support
2,142 thou. CZK
Other public sources
0 thou. CZK
Non public and foreign sources
850 thou. CZK
Recognised costs
2 992 CZK thou.
Public support
2 142 CZK thou.
0%
Provider
Ministry of Education, Youth and Sports
CEP
CB - Analytical chemistry, separation
Solution period
01. 03. 2012 - 31. 12. 2015