All

What are you looking for?

All
Projects
Results
Organizations

Quick search

  • Projects supported by TA ČR
  • Excellent projects
  • Projects with the highest public support
  • Current projects

Smart search

  • That is how I find a specific +word
  • That is how I leave the -word out of the results
  • “That is how I can find the whole phrase”
LH14255

Mechanisms of propagation and crossprotection among viroids infecting hop and apple and their influence on regulation of metabolite pathways of medicinal prenylflavonoids and lupulin.

Public support

  • Provider

    Ministry of Education, Youth and Sports

  • Programme

    KONTAKT II

  • Call for proposals

    KONTAKT II 4 (SMSM2014LH4)

  • Main participants

    Biologické centrum AV ČR, v. v. i.

  • Contest type

    VS - Public tender

  • Contract ID

    MSMT-9919/2014-1

Alternative language

  • Project name in Czech

    Mechanismy propagace a cross protekce u skupiny viroidů chmele a jabloní a jejich vliv na regulaci metabolické dráhy ozdravných prenylflavonoidů a lupulinu

  • Annotation in Czech

    Hlavním účelem projektu je analýza kombinací infekcí u skupiny viroidů z čeledi Pospiviroidae infikujících chmel a ovocné dřeviny; cílem projektu je do jeho dokončení charakterizovat souběžnou propagaci těchto patogenů, kompatibilitu, spektra variant a možné synergistické vlivy na projevy patogeneze s ohledem na mechanismy genového silencingu, ovlivnění exprese regulačních faktorů metabolomu u chmelu a exprese potenciálních cílových mRNA předpověděných bioinformatickými metodami.

Scientific branches

  • R&D category

    ZV - Basic research

  • CEP classification - main branch

    EB - Genetics and molecular biology

  • CEP - secondary branch

    ED - Physiology

  • CEP - another secondary branch

    GF - Diseases, pests, weeds and plant protection

  • OECD FORD - equivalent branches <br>(according to the <a href="http://www.vyzkum.cz/storage/att/E6EF7938F0E854BAE520AC119FB22E8D/Prevodnik_oboru_Frascati.pdf">converter</a>)

    10603 - Genetics and heredity (medical genetics to be 3)<br>10604 - Reproductive biology (medical aspects to be 3)<br>10605 - Developmental biology<br>10608 - Biochemistry and molecular biology<br>10609 - Biochemical research methods<br>30101 - Human genetics<br>30105 - Physiology (including cytology)<br>40106 - Agronomy, plant breeding and plant protection; (Agricultural biotechnology to be 4.4)

Completed project evaluation

  • Provider evaluation

    V - Vynikající výsledky projektu (s mezinárodním významem atd.)

  • Project results evaluation

    Project analyzed combinatorial infections and developed diagnostic of hop viroids. Experiments revealed real risk of multiple infections causing high mortality of hop during dormancy and quantitative instability of viroid propagation. Suppression of microRNA and important lupulin genes as indirect targets; disbalancing of regulatory complexes due to pathogenesis and stimulation of transcription factors from WRKY family connected to plant defense was found

Solution timeline

  • Realization period - beginning

    Apr 1, 2014

  • Realization period - end

    Mar 31, 2016

  • Project status

    U - Finished project

  • Latest support payment

    Feb 18, 2016

Data delivery to CEP

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

  • Data delivery code

    CEP17-MSM-LH-U/01:1

  • Data delivery date

    Jun 23, 2017

Finance

  • Total approved costs

    1,454 thou. CZK

  • Public financial support

    1,454 thou. CZK

  • Other public sources

    0 thou. CZK

  • Non public and foreign sources

    0 thou. CZK