NO signaling during early embryogenesis and regeneration
Public support
Provider
Ministry of Education, Youth and Sports
Programme
NAVRAT
Call for proposals
NÁVRAT 2 (SMSM2013LK2)
Main participants
Biotechnologický ústav AV ČR, v. v. i.
Contest type
VS - Public tender
Contract ID
MSMT-696/2013
Alternative language
Project name in Czech
NO signalizace během časného vývoje a regenerace
Annotation in Czech
1. Signalizace oxidu dusnatého (NO). Identifikace a funkce kandidátních genů, jejichž exprese je regulována NO, 2. Úloha NO během vývoje a zejména při formování epiteliální tkáně pokožky, 3. NO při léčbě poranění.
Scientific branches
R&D category
ZV - Basic research
CEP classification - main branch
EB - Genetics and molecular biology
CEP - secondary branch
—
CEP - another secondary branch
—
OECD FORD - equivalent branches <br>(according to the <a href="http://www.vyzkum.cz/storage/att/E6EF7938F0E854BAE520AC119FB22E8D/Prevodnik_oboru_Frascati.pdf">converter</a>)
10603 - Genetics and heredity (medical genetics to be 3)<br>10604 - Reproductive biology (medical aspects to be 3)<br>10605 - Developmental biology<br>10608 - Biochemistry and molecular biology<br>10609 - Biochemical research methods<br>30101 - Human genetics
Completed project evaluation
Provider evaluation
U - Uspěl podle zadání (s publikovanými či patentovanými výsledky atd.)
Project results evaluation
Project studied role of nitric oxide (NO) during development and after injury. Numerous genes have been found which expression is regulated by NO and majority of them were related to epidermis development. NO inhibition lead to defects in skin formation and strong reduction of ciliated and secretory cells. NO is strongly produced and required during wound healing and regeneration.
Solution timeline
Realization period - beginning
Feb 1, 2013
Realization period - end
Dec 31, 2015
Project status
U - Finished project
Latest support payment
Feb 3, 2014
Data delivery to CEP
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data delivery code
CEP16-MSM-LK-U/01:1
Data delivery date
Jan 25, 2018
Finance
Total approved costs
9,129 thou. CZK
Public financial support
9,129 thou. CZK
Other public sources
0 thou. CZK
Non public and foreign sources
0 thou. CZK