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ME 176

Evolutionary conserved mechanisms underlying tissue-specific gene expression

Project goals

Evolutionary conserved mechanisms of tissue specific gene expression: Project is aimed on the evolutionary conserved mechanisms of tissue specific gene expression. The labial glands of insects (the salivary gland of Drosophila and the silk gland of Bombyx) will serve as a model to investigate the mechanisms ensuring expression of abundant and tissue specific genes in the labial gland. These mechanisms supposingly differ from the mechanisms governing the less abundant transcription of genes expressed both in the labial gland and other tissues.

Keywords

gene transcriptionFork headDrosophilasalivary glandtissue -specific

Public support

  • Provider

    Ministry of Education, Youth and Sports

  • Programme

    KONTAKT

  • Call for proposals

  • Main participants

    Entomologický ústav AV ČR

  • Contest type

  • Contract ID

Alternative language

  • Project name in Czech

    Evolučně konzervované mechanismy tkáňově specifické exprese genu.

  • Annotation in Czech

    Projekt je zaměřen na evoluční konzervování mechanismy tkáňově specifického přepisu genu. Na modelu labiálních žláz hmyzu bude ověřována hypotéza že přepis genu s tkáňovou specificitou a genu exprimovaných ve více tkáních je zajištěn odlišnými mechanismy.

Scientific branches

  • R&D category

  • CEP classification - main branch

    EB - Genetics and molecular biology

  • CEP - secondary branch

  • CEP - another secondary branch

  • 10603 - Genetics and heredity (medical genetics to be 3)
    10604 - Reproductive biology (medical aspects to be 3)
    10605 - Developmental biology
    10608 - Biochemistry and molecular biology
    10609 - Biochemical research methods
    30101 - Human genetics

Completed project evaluation

  • Provider evaluation

    U - Uspěl podle zadání (s publikovanými či patentovanými výsledky atd.)

  • Project results evaluation

    Zaklonování částečných c DNA Fork head homologů, průkaz přítomnosti těchto proteinů v extraktech, detailní studium rozdílů ve vazebné specifitě Fork head proteinů Drosophila melanogester, Bombyx mori, Drosophila virilis a Galleria mellonela.

Solution timeline

  • Realization period - beginning

    Jan 1, 1998

  • Realization period - end

    Jan 1, 2000

  • Project status

    U - Finished project

  • Latest support payment

Data delivery to CEP

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

  • Data delivery code

    CEP/2001/MSM/MSM1ME/U/N/2:1

  • Data delivery date

Finance

  • Total approved costs

    1,770 thou. CZK

  • Public financial support

    570 thou. CZK

  • Other public sources

    0 thou. CZK

  • Non public and foreign sources

    0 thou. CZK

Basic information

Recognised costs

1 770 CZK thou.

Public support

570 CZK thou.

32%


Provider

Ministry of Education, Youth and Sports

CEP

EB - Genetics and molecular biology

Solution period

01. 01. 1998 - 01. 01. 2000