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ME 849

Antiproliferative effects of bilirubin, heme metabolites, and heme oxygenase expression on colon and pancreatic cancer.

Public support

  • Provider

    Ministry of Education, Youth and Sports

  • Programme

    KONTAKT

  • Call for proposals

    KONTAKT 4 (SMSM200600ME1)

  • Main participants

  • Contest type

    VS - Public tender

  • Contract ID

    2783/2009-32

Alternative language

  • Project name in Czech

    Antiproliferační účinky bilirubinu, metabolitů hemu a exprese hemoxygenázy na karcinomu tlustého střeva a pankreatu

  • Annotation in Czech

    detailní studium úlohy metabolismu bilirubinu v patogenezi kolorektálního a pankreatického karcinomu, základní výzkum, dataázový výzkum

Scientific branches

  • R&D category

    AP - Applied research

  • CEP classification - main branch

    FD - Oncology and haematology

  • CEP - secondary branch

  • CEP - another secondary branch

  • OECD FORD - equivalent branches <br>(according to the <a href="http://www.vyzkum.cz/storage/att/E6EF7938F0E854BAE520AC119FB22E8D/Prevodnik_oboru_Frascati.pdf">converter</a>)

    30204 - Oncology<br>30205 - Hematology

Completed project evaluation

  • Provider evaluation

    V - Vynikající výsledky projektu (s mezinárodním významem atd.)

  • Project results evaluation

    Novel methods for investigation of bile pigment metabolism were stablished. Anticancer effects of bile pigments and carbon monoxide were proved on experimental models of pancreatic cancer. Relationship between genes controlling sérum bilirubin levels andcolon cancer risk was elucidated.

Solution timeline

  • Realization period - beginning

    Mar 1, 2006

  • Realization period - end

    Mar 31, 2009

  • Project status

    U - Finished project

  • Latest support payment

    Feb 24, 2009

Data delivery to CEP

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

  • Data delivery code

    CEP10-MSM-ME-U/01:1

  • Data delivery date

    Jun 30, 2010

Finance

  • Total approved costs

    2,890 thou. CZK

  • Public financial support

    2,770 thou. CZK

  • Other public sources

    0 thou. CZK

  • Non public and foreign sources

    120 thou. CZK