Structure-activity study and mechanism of action of analogues of humanin, a novel neuroprotective petide
Public support
Provider
Ministry of Education, Youth and Sports
Programme
KONTAKT
Call for proposals
KONTAKT 4 (SMSM200600ME1)
Main participants
—
Contest type
VS - Public tender
Contract ID
1 016/2006-32
Alternative language
Project name in Czech
Strukturně aktivní studia a mechanismus účinků analogů humaninu, nového neuroprotektivního peptidu
Annotation in Czech
poznání biologické funkce humaninu, nového peptidu, jeho modifikace, vývoj nových léčiv
Scientific branches
R&D category
NV - Nonindustrial research (Applied research excluded Industrial research)
CEP classification - main branch
CC - Organic chemistry
CEP - secondary branch
—
CEP - another secondary branch
—
OECD FORD - equivalent branches <br>(according to the <a href="http://www.vyzkum.cz/storage/att/E6EF7938F0E854BAE520AC119FB22E8D/Prevodnik_oboru_Frascati.pdf">converter</a>)
10401 - Organic chemistry
Completed project evaluation
Provider evaluation
V - Vynikající výsledky projektu (s mezinárodním významem atd.)
Project results evaluation
New analogues of humanin were tested in vivo for their influence on memory and spacial orientation after intraperitoneal application with rat (T-maze test). Several of the tested compounds showed a positive effect in this test.
Solution timeline
Realization period - beginning
Mar 1, 2006
Realization period - end
Mar 31, 2007
Project status
U - Finished project
Latest support payment
Mar 26, 2007
Data delivery to CEP
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data delivery code
CEP08-MSM-ME-U/02:2
Data delivery date
Oct 27, 2008
Finance
Total approved costs
180 thou. CZK
Public financial support
180 thou. CZK
Other public sources
0 thou. CZK
Non public and foreign sources
0 thou. CZK