Srs2 protein and its multifunctional role in recombination/repair processes
Public support
Provider
Ministry of Education, Youth and Sports
Programme
KONTAKT
Call for proposals
KONTAKT 4 (SMSM200600ME1)
Main participants
—
Contest type
VS - Public tender
Contract ID
1 016/2006-32
Alternative language
Project name in Czech
Srs2 protein a jeho multifunkční úloha při rekombinančních /opravných procesech
Annotation in Czech
charakterizace anti-rekombinanční aktivity proteinu Srs2, jeho úloha při replikaci a syntéze DNA, regulace jeho aktivity
Scientific branches
R&D category
NV - Nonindustrial research (Applied research excluded Industrial research)
CEP classification - main branch
EI - Biotechnology and bionics
CEP - secondary branch
—
CEP - another secondary branch
—
OECD FORD - equivalent branches <br>(according to the <a href="http://www.vyzkum.cz/storage/att/E6EF7938F0E854BAE520AC119FB22E8D/Prevodnik_oboru_Frascati.pdf">converter</a>)
20801 - Environmental biotechnology<br>20802 - Bioremediation, diagnostic biotechnologies (DNA chips and biosensing devices) in environmental management<br>20803 - Environmental biotechnology related ethics<br>20901 - Industrial biotechnology<br>20902 - Bioprocessing technologies (industrial processes relying on biological agents to drive the process) biocatalysis, fermentation<br>20903 - Bioproducts (products that are manufactured using biological material as feedstock) biomaterials, bioplastics, biofuels, bioderived bulk and fine chemicals, bio-derived novel materials<br>30401 - Health-related biotechnology<br>30402 - Technologies involving the manipulation of cells, tissues, organs or the whole organism (assisted reproduction)<br>30403 - Technologies involving identifying the functioning of DNA, proteins and enzymes and how they influence the onset of disease and maintenance of well-being (gene-based diagnostics and therapeutic interventions [pharmacogenomics, gene-based therapeutics])<br>30404 - Biomaterials (as related to medical implants, devices, sensors)<br>30405 - Medical biotechnology related ethics<br>40401 - Agricultural biotechnology and food biotechnology<br>40402 - GM technology (crops and livestock), livestock cloning, marker assisted selection, diagnostics (DNA chips and biosensing devices for the early/accurate detection of diseases) biomass feedstock production technologies, biopharming<br>40403 - Agricultural biotechnology related ethics
Completed project evaluation
Provider evaluation
U - Uspěl podle zadání (s publikovanými či patentovanými výsledky atd.)
Project results evaluation
Homologous recombination plays crucial role in repair of DNA breaks. We focused on molecular dissection of Rad52 stimulator as well as Srs2 inhibitor of HR. Our results led to formulation of HR quality control mechanism and were published.
Solution timeline
Realization period - beginning
Mar 1, 2006
Realization period - end
Feb 29, 2008
Project status
U - Finished project
Latest support payment
Feb 29, 2008
Data delivery to CEP
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data delivery code
CEP09-MSM-ME-U/02:2
Data delivery date
May 7, 2010
Finance
Total approved costs
6,586 thou. CZK
Public financial support
2,200 thou. CZK
Other public sources
0 thou. CZK
Non public and foreign sources
4,386 thou. CZK