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ME08017

Platinum Metal Complexes as DNA-Protein Cross-Linking Agents

Public support

  • Provider

    Ministry of Education, Youth and Sports

  • Programme

    KONTAKT

  • Call for proposals

    KONTAKT 6 (SMSM2008ME3)

  • Main participants

  • Contest type

    VS - Public tender

  • Contract ID

    1323/2010-32

Alternative language

  • Project name in Czech

    Komplexy platiny jako agens vhodná pro vytváření můstků mezi DNA a bílkovinami

  • Annotation in Czech

    Cílem tohoto výzkumu je zjistit údaje o kovalentních interakcích DNA modifikované komplexy platiny s proteiny.

Scientific branches

  • R&D category

    ZV - Basic research

  • CEP classification - main branch

    BO - Biophysics

  • CEP - secondary branch

    CE - Biochemistry

  • CEP - another secondary branch

    FR - Pharmacology and apothecary chemistry

  • OECD FORD - equivalent branches <br>(according to the <a href="http://www.vyzkum.cz/storage/att/E6EF7938F0E854BAE520AC119FB22E8D/Prevodnik_oboru_Frascati.pdf">converter</a>)

    10608 - Biochemistry and molecular biology<br>10609 - Biochemical research methods<br>10610 - Biophysics<br>30104 - Pharmacology and pharmacy

Completed project evaluation

  • Provider evaluation

    V - Vynikající výsledky projektu (s mezinárodním významem atd.)

  • Project results evaluation

    Joint and complementary studies with a US laboratory provided results demonstrating that transition-metal based complexes can be used as agents capable of forming cross-links between DNA and proteins. The implementation of this project made it posible toparticipate in the international cooperation in R&D based on the agreement on the scientific and technical cooperation with the NSF (USA).

Solution timeline

  • Realization period - beginning

    Jan 1, 2008

  • Realization period - end

    Dec 31, 2010

  • Project status

    U - Finished project

  • Latest support payment

    Mar 1, 2010

Data delivery to CEP

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

  • Data delivery code

    CEP11-MSM-ME-U/01:1

  • Data delivery date

    Jun 30, 2011

Finance

  • Total approved costs

    2,226 thou. CZK

  • Public financial support

    2,226 thou. CZK

  • Other public sources

    0 thou. CZK

  • Non public and foreign sources

    0 thou. CZK