The role of post-transtranional mechanisms in reprogramming of mouse oocytes into pluripotent cells
Public support
Provider
Ministry of Education, Youth and Sports
Programme
KONTAKT
Call for proposals
KONTAKT 7 (SMSM2009ME4)
Main participants
—
Contest type
VS - Public tender
Contract ID
2060/2011-320
Alternative language
Project name in Czech
Role post-transkripčních mechanismů v reprogramování myších oocytů na pluripotentní buňky
Annotation in Czech
Lépe pochopit roli post-transkripčních mechanismů v přeprogramování genové exprese oocytu na program pluripotentních buněk myšího embrya. Zjednodušeně řečeno, jedná se o studium počátku procesu, kterým z ovulovaného vajíčka vznikne celý organismus.
Scientific branches
R&D category
ZV - Basic research
CEP classification - main branch
EB - Genetics and molecular biology
CEP - secondary branch
EI - Biotechnology and bionics
CEP - another secondary branch
—
OECD FORD - equivalent branches <br>(according to the <a href="http://www.vyzkum.cz/storage/att/E6EF7938F0E854BAE520AC119FB22E8D/Prevodnik_oboru_Frascati.pdf">converter</a>)
10603 - Genetics and heredity (medical genetics to be 3)<br>10604 - Reproductive biology (medical aspects to be 3)<br>10605 - Developmental biology<br>10608 - Biochemistry and molecular biology<br>10609 - Biochemical research methods<br>20801 - Environmental biotechnology<br>20802 - Bioremediation, diagnostic biotechnologies (DNA chips and biosensing devices) in environmental management<br>20803 - Environmental biotechnology related ethics<br>20901 - Industrial biotechnology<br>20902 - Bioprocessing technologies (industrial processes relying on biological agents to drive the process) biocatalysis, fermentation<br>20903 - Bioproducts (products that are manufactured using biological material as feedstock) biomaterials, bioplastics, biofuels, bioderived bulk and fine chemicals, bio-derived novel materials<br>30101 - Human genetics<br>30401 - Health-related biotechnology<br>30402 - Technologies involving the manipulation of cells, tissues, organs or the whole organism (assisted reproduction)<br>30403 - Technologies involving identifying the functioning of DNA, proteins and enzymes and how they influence the onset of disease and maintenance of well-being (gene-based diagnostics and therapeutic interventions [pharmacogenomics, gene-based therapeutics])<br>30404 - Biomaterials (as related to medical implants, devices, sensors)<br>30405 - Medical biotechnology related ethics<br>40401 - Agricultural biotechnology and food biotechnology<br>40402 - GM technology (crops and livestock), livestock cloning, marker assisted selection, diagnostics (DNA chips and biosensing devices for the early/accurate detection of diseases) biomass feedstock production technologies, biopharming<br>40403 - Agricultural biotechnology related ethics
Completed project evaluation
Provider evaluation
V - Vynikající výsledky projektu (s mezinárodním významem atd.)
Project results evaluation
A four year collaborative project between groups of Dr. Petr Svoboda (Institute of Molecular Genetics ASCR) and prof. Richard M. Schultz University of Pennsylvania has achieved its goal: to understand the role of selected post-transcriptional mechanism in genome reprogramming during the oocyte-to-zygote transition. A number of discoveries was made, which were published in scientific journals.
Solution timeline
Realization period - beginning
Apr 1, 2009
Realization period - end
Dec 31, 2012
Project status
U - Finished project
Latest support payment
Feb 23, 2012
Data delivery to CEP
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data delivery code
CEP13-MSM-ME-U/01:1
Data delivery date
Jun 28, 2013
Finance
Total approved costs
2,000 thou. CZK
Public financial support
2,000 thou. CZK
Other public sources
0 thou. CZK
Non public and foreign sources
0 thou. CZK