Development of novel antidotal treatment against organophosphorus pesticides
Public support
Provider
Ministry of Education, Youth and Sports
Programme
KONTAKT
Call for proposals
KONTAKT 7 (SMSM2009ME4)
Main participants
—
Contest type
VS - Public tender
Contract ID
2060/2011-320
Alternative language
Project name in Czech
Vývoj nových antidotních prostředků proti organofosforovým pesticidům
Annotation in Czech
V rámci projektu by měl být nalezen širokospektrý reaktivátor organofosforových pesticidů (OPP) v podmínkách in vitro.
Scientific branches
R&D category
ZV - Basic research
CEP classification - main branch
FR - Pharmacology and apothecary chemistry
CEP - secondary branch
CC - Organic chemistry
CEP - another secondary branch
CE - Biochemistry
OECD FORD - equivalent branches <br>(according to the <a href="http://www.vyzkum.cz/storage/att/E6EF7938F0E854BAE520AC119FB22E8D/Prevodnik_oboru_Frascati.pdf">converter</a>)
10401 - Organic chemistry<br>10608 - Biochemistry and molecular biology<br>10609 - Biochemical research methods<br>30104 - Pharmacology and pharmacy
Completed project evaluation
Provider evaluation
V - Vynikající výsledky projektu (s mezinárodním významem atd.)
Project results evaluation
Project ME09086 (2009-2012) was focused on synthesis, evaluation and structure-activity determination of acetylcholinesterase reactivators counteracting organophosphorus pesticides. 56 novel compounds were prepared and over 100 acetylcholinesterase reactivators tested. Compound K027 was recommended as broad spectrum reactivator candidate against organophosphorus pesticides intoxication.
Solution timeline
Realization period - beginning
Apr 1, 2009
Realization period - end
Dec 31, 2012
Project status
U - Finished project
Latest support payment
Feb 23, 2012
Data delivery to CEP
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data delivery code
CEP13-MSM-ME-U/01:1
Data delivery date
Jun 28, 2013
Finance
Total approved costs
1,692 thou. CZK
Public financial support
1,692 thou. CZK
Other public sources
0 thou. CZK
Non public and foreign sources
0 thou. CZK