Characterization of T and B lymphocytes in Ileal Peyers Patches of swine.
Public support
Provider
Ministry of Education, Youth and Sports
Programme
KONTAKT
Call for proposals
KONTAKT 7 (SMSM2009ME4)
Main participants
—
Contest type
VS - Public tender
Contract ID
2060/2011-320
Alternative language
Project name in Czech
Charakterizace T a B lymfocytů v Peyerských placích kyčelníku u prasete
Annotation in Czech
Cílem tohoto projektu je odhalit a objasnit fenotyp, četnost, vývoj, aktivační potenciál, lokalizaci a rozmanitost receptorů pro T a B lymfocyty v IPP prasete a jakou roli hraje v tomto ohledu antigenní stimulace, kolonizace trávícího traktu a výživa.
Scientific branches
R&D category
ZV - Basic research
CEP classification - main branch
EC - Immunology
CEP - secondary branch
EB - Genetics and molecular biology
CEP - another secondary branch
GJ - Diseases and animal vermin, veterinary medicine
OECD FORD - equivalent branches <br>(according to the <a href="http://www.vyzkum.cz/storage/att/E6EF7938F0E854BAE520AC119FB22E8D/Prevodnik_oboru_Frascati.pdf">converter</a>)
10603 - Genetics and heredity (medical genetics to be 3)<br>10604 - Reproductive biology (medical aspects to be 3)<br>10605 - Developmental biology<br>10608 - Biochemistry and molecular biology<br>10609 - Biochemical research methods<br>30101 - Human genetics<br>30102 - Immunology<br>40301 - Veterinary science
Completed project evaluation
Provider evaluation
V - Vynikající výsledky projektu (s mezinárodním významem atd.)
Project results evaluation
Analysis of lymphocytes in swine Ileal Payer's Patches (IPP) showed that IPP are not critical for the development of B. On the other hand, the bone marrow was shown as a site of B cell lymphogenesis. These findings imply that development of B cells occurs in the bone marrow while IPP serve as a site of B cell diversification which is relevant but not crucial for mucosal immunity.
Solution timeline
Realization period - beginning
Apr 1, 2009
Realization period - end
Dec 31, 2012
Project status
U - Finished project
Latest support payment
Feb 23, 2012
Data delivery to CEP
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data delivery code
CEP13-MSM-ME-U/01:1
Data delivery date
Jun 28, 2013
Finance
Total approved costs
3,738 thou. CZK
Public financial support
3,738 thou. CZK
Other public sources
0 thou. CZK
Non public and foreign sources
0 thou. CZK