Cooperative contribution of actin- and myosin-families to the chromatin dynamics and tranion in the cell nucleus
Public support
Provider
Ministry of Education, Youth and Sports
Programme
KONTAKT
Call for proposals
KONTAKT 7 (SMSM2009ME4)
Main participants
—
Contest type
VS - Public tender
Contract ID
1324/2010-32
Alternative language
Project name in Czech
Příspěvek proteinových rodin aktinu a myosinu k dynamice a transkripci chromatinu v buněčném jádře.
Annotation in Czech
Zjištění principů spolupráce proteinů Arp6 a NM1 ve funkční organizaci buněčného jádra a chromatinu, především pak jejich příspěvek k organizaci chromozomů v jádře, dynamice pohybu chromatinu a tvorbě chromatinu schopného přepisu genetické informace.
Scientific branches
R&D category
ZV - Basic research
CEP classification - main branch
EB - Genetics and molecular biology
CEP - secondary branch
CE - Biochemistry
CEP - another secondary branch
—
OECD FORD - equivalent branches <br>(according to the <a href="http://www.vyzkum.cz/storage/att/E6EF7938F0E854BAE520AC119FB22E8D/Prevodnik_oboru_Frascati.pdf">converter</a>)
10603 - Genetics and heredity (medical genetics to be 3)<br>10604 - Reproductive biology (medical aspects to be 3)<br>10605 - Developmental biology<br>10608 - Biochemistry and molecular biology<br>10609 - Biochemical research methods<br>30101 - Human genetics
Completed project evaluation
Provider evaluation
U - Uspěl podle zadání (s publikovanými či patentovanými výsledky atd.)
Project results evaluation
The project described interactions between Arp proteins and the nuclear myosin I (NM1,) and their functions in organization of the nuclear interior. Special cell lines deficient for Arps/NM1 were developed. New data were acquired (2 published articles, 1manuscript, 1 manuin preparation, 3 conference presentations) the project also improved intensified studies of our PhD students
Solution timeline
Realization period - beginning
Apr 1, 2009
Realization period - end
Dec 31, 2010
Project status
U - Finished project
Latest support payment
Mar 2, 2010
Data delivery to CEP
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data delivery code
CEP11-MSM-ME-U/01:1
Data delivery date
Jun 30, 2011
Finance
Total approved costs
1,336 thou. CZK
Public financial support
1,336 thou. CZK
Other public sources
0 thou. CZK
Non public and foreign sources
0 thou. CZK