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Quality evaluation of nano-coating made from noble metals covered ceramic implants in alive organism and environment of artificial cultivated tissue

Public support

  • Provider

    Ministry of Education, Youth and Sports

  • Programme

    KONTAKT

  • Call for proposals

  • Main participants

  • Contest type

    M2 - International cooperation

  • Contract ID

    22829/2010-32

Alternative language

  • Project name in Czech

    Hodnocení kvality keramických implantátů s nano vrstvou z ušlechtilých kovů v živém organismu a okolí kultivovaných buněk

  • Annotation in Czech

    Projekt je zaměřen na sledování biokompatibility a hodnocení změn na povrchu keramických implantátů potažených nano vrstvou z ušlechtilých kovů. Použity budou primární kultury fibroblastů a osteoblastů a aplikace in vivo u potkana. In vitro budou hodnoceny základní parametry - životnost a proliferace a exprese adhesivních proteinů (vinkulin, integrin, u experimentů in vivo bude provedena histologická analýza tkáně v okolí implantátu a analyzována korosita materiálů.

Scientific branches

  • R&D category

    ZV - Basic research

  • CEP classification - main branch

    FP - Other medical fields

  • CEP - secondary branch

    CE - Biochemistry

  • CEP - another secondary branch

  • OECD FORD - equivalent branches <br>(according to the <a href="http://www.vyzkum.cz/storage/att/E6EF7938F0E854BAE520AC119FB22E8D/Prevodnik_oboru_Frascati.pdf">converter</a>)

    10608 - Biochemistry and molecular biology<br>10609 - Biochemical research methods<br>30106 - Anatomy and morphology (plant science to be 1.6)<br>30107 - Medicinal chemistry<br>30108 - Toxicology<br>30109 - Pathology<br>30221 - Critical care medicine and Emergency medicine<br>30223 - Anaesthesiology<br>30224 - Radiology, nuclear medicine and medical imaging<br>30225 - Allergy<br>30226 - Rheumatology<br>30227 - Geriatrics and gerontology<br>30229 - Integrative and complementary medicine (alternative practice systems)<br>30230 - Other clinical medicine subjects<br>30307 - Nursing<br>30308 - Nutrition, Dietetics<br>30309 - Tropical medicine<br>30310 - Parasitology<br>30311 - Medical ethics<br>30312 - Substance abuse<br>30501 - Forensic science<br>30502 - Other medical science

Completed project evaluation

  • Provider evaluation

    U - Uspěl podle zadání (s publikovanými či patentovanými výsledky atd.)

  • Project results evaluation

    Obtained results confirm good tolerance and quality of the gold coating with a thickness of 10 microns on the base material - zirconium oxyde in the experiment by animal cells, both in cell culture and in vivo studies.

Solution timeline

  • Realization period - beginning

    Jan 1, 2010

  • Realization period - end

    Dec 31, 2011

  • Project status

    U - Finished project

  • Latest support payment

    Mar 7, 2011

Data delivery to CEP

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

  • Data delivery code

    CEP12-MSM-ME-U/01:1

  • Data delivery date

    Jul 12, 2012

Finance

  • Total approved costs

    68 thou. CZK

  • Public financial support

    68 thou. CZK

  • Other public sources

    0 thou. CZK

  • Non public and foreign sources

    0 thou. CZK