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Studies of mutant mice with a lack of anchoring protein cholinesterase, PRIMA

Public support

  • Provider

    Ministry of Education, Youth and Sports

  • Programme

    KONTAKT

  • Call for proposals

  • Main participants

  • Contest type

    M2 - International cooperation

  • Contract ID

    5242/2010-32

Alternative language

  • Project name in Czech

    Studium mutantních myší s chybějícím kotvícím proteinem cholinesteráz, PRiMA

  • Annotation in Czech

    Zjistit, které receprotové systémy se podílejí na adaptačních mechanismech zodpovědných za přežívání myší s nulovou aktivitou acetylcholinestrázy. Výsledek umožní rozšířit poznání o neurodegenerativních chorobách a jejich léčbě.

Scientific branches

  • R&D category

    ZV - Basic research

  • CEP classification - main branch

    ED - Physiology

  • CEP - secondary branch

    FH - Neurology, neuro-surgery, nuero-sciences

  • CEP - another secondary branch

  • OECD FORD - equivalent branches <br>(according to the <a href="http://www.vyzkum.cz/storage/att/E6EF7938F0E854BAE520AC119FB22E8D/Prevodnik_oboru_Frascati.pdf">converter</a>)

    30103 - Neurosciences (including psychophysiology)<br>30105 - Physiology (including cytology)<br>30210 - Clinical neurology

Completed project evaluation

  • Provider evaluation

    U - Uspěl podle zadání (s publikovanými či patentovanými výsledky atd.)

  • Project results evaluation

    Thanks this grant we have published 2 articles and presented 11 leactures on conferences. We have found that although there is 500 time higher level of acetylcholine in PRiMA mice than in WR, there is no functional differences. The homeostasis is achivedvia muscarinic receptors.

Solution timeline

  • Realization period - beginning

    Jan 1, 2010

  • Realization period - end

    Dec 31, 2011

  • Project status

    U - Finished project

  • Latest support payment

    Mar 2, 2011

Data delivery to CEP

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

  • Data delivery code

    CEP12-MSM-ME-U/01:1

  • Data delivery date

    Jul 12, 2012

Finance

  • Total approved costs

    60 thou. CZK

  • Public financial support

    60 thou. CZK

  • Other public sources

    0 thou. CZK

  • Non public and foreign sources

    0 thou. CZK