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NB7611

Effect of growth hormone and glutamine on protein metabolism in isolated skeletal muscle.

Public support

  • Provider

    Ministry of Health

  • Programme

    Research and development in the sphere of nutrition, metabolic and endocrine diseases

  • Call for proposals

    Výzkum a vývoj v oblasti Kardiovaskulárních chorob 5 (SMZ02003NB)

  • Main participants

    Univerzita Karlova / Lékařská fakulta v Hradci Králové

  • Contest type

    VS - Public tender

  • Contract ID

Alternative language

  • Project name in Czech

    Vliv růstového hormonu a glutaminu na metabolizmus proteinů v izolovaném kosterním svalu.

  • Annotation in Czech

    Možnosti ovlivňování proteokatabolizmu pomocí růstového hormonu a glutaminu u pacientů budou studovány metodou inkubace izolovaných kosterních svalů laboratorního potkana. Hlavní parametry metabolizmu proteinů budou hodnoceny pomocí radioizotopů.

Scientific branches

  • R&D category

    NV - Nonindustrial research (Applied research excluded Industrial research)

  • CEP classification - main branch

    FB - Endocrinology, diabetology, metabolism, nutrition

  • CEP - secondary branch

  • CEP - another secondary branch

  • OECD FORD - equivalent branches <br>(according to the <a href="http://www.vyzkum.cz/storage/att/E6EF7938F0E854BAE520AC119FB22E8D/Prevodnik_oboru_Frascati.pdf">converter</a>)

    30202 - Endocrinology and metabolism (including diabetes, hormones)

Completed project evaluation

  • Provider evaluation

    V - Vynikající výsledky projektu (s mezinárodním významem atd.)

  • Project results evaluation

    Glutamine deficiency in sepsis together with growth hormone administration has negative effects on metabolism of proteins,glutamine and branched-chain amino acids.Administration of glutamine and proteasome inhibitors in septic states is beneficial.

Solution timeline

  • Realization period - beginning

    Jan 1, 2003

  • Realization period - end

    Jan 1, 2005

  • Project status

    U - Finished project

  • Latest support payment

Data delivery to CEP

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

  • Data delivery code

    CEP06-MZ0-NB-U/01:1

  • Data delivery date

    Jun 23, 2006

Finance

  • Total approved costs

    934 thou. CZK

  • Public financial support

    931 thou. CZK

  • Other public sources

    0 thou. CZK

  • Non public and foreign sources

    0 thou. CZK