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NC6610

Study of expression and activation of apoptogenic caspases and of levels of their inhibitors in non-small cell lung carcinoma

Project goals

Study of expression and activation of apoptogennic caspases and of levels of their inhibitors XIAP and survivin in human non-small cell lung carcinoma with the aim to evaluate their correlation with progression of this cancer disease.

Keywords

non-small cell lung carcinomatumor progressiontumor cell apoptosisApaf-1caspase -9caspase-3caspase-6caspase-7

Public support

  • Provider

    Ministry of Health

  • Programme

    Research and development in the sphere of oncology

  • Call for proposals

    Výzkum a vývoj v oblasti Kardiovaskulárních chorob 9 (SMZ0NC2001)

  • Main participants

    Fakultní nemocnice Bulovka

  • Contest type

    VS - Public tender

  • Contract ID

Alternative language

  • Project name in Czech

    Studium exprese a aktivace apoptogenních kaspas a hladin jejich inhibitorů u nemalobuněčného karcinomu plic

  • Annotation in Czech

    Studium exprese a aktivace apoptogenních kaspas a hladin jejich bílkovinných inhibitorů u nemalobuněčného karcinomu plic člověka a určení jejich významu pro progresi tohoto nádorového onemocnění.

Scientific branches

  • R&D category

  • CEP classification - main branch

    FD - Oncology and haematology

  • CEP - secondary branch

  • CEP - another secondary branch

  • 30204 - Oncology
    30205 - Hematology

Completed project evaluation

  • Provider evaluation

    V - Vynikající výsledky projektu (s mezinárodním významem atd.)

  • Project results evaluation

    Rozdíly v aktivaci cysteinových proteináz při apoptóze.

Solution timeline

  • Realization period - beginning

    Jan 1, 2001

  • Realization period - end

    Jan 1, 2003

  • Project status

    U - Finished project

  • Latest support payment

Data delivery to CEP

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

  • Data delivery code

    CEP/2004/MZ0/MZ04NC/U/N/3:1

  • Data delivery date

    Jul 12, 2004

Finance

  • Total approved costs

    3,500 thou. CZK

  • Public financial support

    3,470 thou. CZK

  • Other public sources

    0 thou. CZK

  • Non public and foreign sources

    0 thou. CZK

Recognised costs

3 500 CZK thou.

Public support

3 470 CZK thou.

0%


Provider

Ministry of Health

CEP

FD - Oncology and haematology

Solution period

01. 01. 2001 - 01. 01. 2003