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NM7719

Thrombotic thrombocytopenic purpura: molecular-biological diagnosis

Public support

  • Provider

    Ministry of Health

  • Programme

    Implementation of molecular biological methods in diagnostics and treatment

  • Call for proposals

    Implementace molekulárně-biologických metod v diagnostice a léčbě 2 (SMZ02003NM)

  • Main participants

    Ústav hematologie a krevní transfúze

  • Contest type

    VS - Public tender

  • Contract ID

Alternative language

  • Project name in Czech

    Molekulárně-biologická diagnostika trombotické trombocytopenické purpury.

  • Annotation in Czech

    V rámci molekulárně-genetické diagnostiky TTP budeme zavádět metodiky na stanovení aktivity depolymerázy VWF a jejího inhibitoru, metodiky na DNA analýzu genu pro depolymerázu (ADAMST13) a hyperkoagulační ukazatele v průběhu remise i onemocnění.

Scientific branches

  • R&D category

    NV - Nonindustrial research (Applied research excluded Industrial research)

  • CEP classification - main branch

    FD - Oncology and haematology

  • CEP - secondary branch

    FE - Other fields of internal medicine

  • CEP - another secondary branch

  • OECD FORD - equivalent branches <br>(according to the <a href="http://www.vyzkum.cz/storage/att/E6EF7938F0E854BAE520AC119FB22E8D/Prevodnik_oboru_Frascati.pdf">converter</a>)

    30204 - Oncology<br>30205 - Hematology<br>30217 - Urology and nephrology<br>30218 - General and internal medicine<br>30219 - Gastroenterology and hepatology<br>30220 - Andrology

Completed project evaluation

  • Provider evaluation

    U - Uspěl podle zadání (s publikovanými či patentovanými výsledky atd.)

  • Project results evaluation

    Molecular-biolog.methods were established for diagnosis of TTP.They were used to distinguish an inherited,acquired TTP and other thrombo-micorangiopat.(HUS).We determined causal mutations of familial TTP and evaluated markers of disease process.

Solution timeline

  • Realization period - beginning

    Jan 1, 2003

  • Realization period - end

    Jan 1, 2005

  • Project status

    U - Finished project

  • Latest support payment

Data delivery to CEP

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

  • Data delivery code

    CEP06-MZ0-NM-U/01:1

  • Data delivery date

    Jun 23, 2006

Finance

  • Total approved costs

    4,718 thou. CZK

  • Public financial support

    4,606 thou. CZK

  • Other public sources

    0 thou. CZK

  • Non public and foreign sources

    0 thou. CZK