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NR7870

Mechanisms of imatinib resistance in patients with chronic myelogenous leukaemia

Public support

  • Provider

    Ministry of Health

  • Programme

    Branch programm of research of the Ministry of Health

  • Call for proposals

    VaV pro Ministerstvo zdravotnictví 1 (SMZ02004NR)

  • Main participants

  • Contest type

    VS - Public tender

  • Contract ID

Alternative language

  • Project name in Czech

    Mechanizmy rezistence na imatinib u nemocných s chronickou myeloidní leukemií

  • Annotation in Czech

    Reziduální subklony leukemických buněk in vitro rezistentní na imatinib, získané od nemocných s Ph+ CML jsou vyšetřovány na kvalitativní a kvantitativní genetické změny technologií CGH mikroarray a sekvenováním ATP domény proteinu BCR/ABL.

Scientific branches

  • R&D category

    NV - Nonindustrial research (Applied research excluded Industrial research)

  • CEP classification - main branch

    FD - Oncology and haematology

  • CEP - secondary branch

  • CEP - another secondary branch

  • OECD FORD - equivalent branches <br>(according to the <a href="http://www.vyzkum.cz/storage/att/E6EF7938F0E854BAE520AC119FB22E8D/Prevodnik_oboru_Frascati.pdf">converter</a>)

    30204 - Oncology<br>30205 - Hematology

Completed project evaluation

  • Provider evaluation

    V - Vynikající výsledky projektu (s mezinárodním významem atd.)

  • Project results evaluation

    Elucidation of the genetic or molecular cause respectively of the resistence to imatinib in some patients with chronic myeloid leukemia

Solution timeline

  • Realization period - beginning

    Jan 1, 2004

  • Realization period - end

    Jan 1, 2006

  • Project status

    U - Finished project

  • Latest support payment

Data delivery to CEP

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

  • Data delivery code

    CEP07-MZ0-NR-U/06:2

  • Data delivery date

    Aug 8, 2007

Finance

  • Total approved costs

    3,370 thou. CZK

  • Public financial support

    3,187 thou. CZK

  • Other public sources

    0 thou. CZK

  • Non public and foreign sources

    130 thou. CZK