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NR7956

A new insight on the role of the renin-angiotensin system in blood pressure regulation and development of hypertension-a study in transgenic rats with inducible hypertension

Public support

  • Provider

    Ministry of Health

  • Programme

    Branch programm of research of the Ministry of Health

  • Call for proposals

    VaV pro Ministerstvo zdravotnictví 1 (SMZ02004NR)

  • Main participants

  • Contest type

    VS - Public tender

  • Contract ID

Alternative language

  • Project name in Czech

    Nový pohled na úlohu renin-angiotenzinového systému v regulaci krevního tlaku a rozvoji hypertenze:studie na transgenních potkanech s indukovatelnou hypertenzí

  • Annotation in Czech

    Bude studována úloha renin-angiotenzinového systému v regulaci krevního tlaku a rozvoji hypertenze na modelu transgenního potkana pro myší gen s indukovatelnou hypertenzí.

Scientific branches

  • R&D category

    NV - Nonindustrial research (Applied research excluded Industrial research)

  • CEP classification - main branch

    FA - Cardiovascular diseases including cardio-surgery

  • CEP - secondary branch

    ED - Physiology

  • CEP - another secondary branch

  • OECD FORD - equivalent branches <br>(according to the <a href="http://www.vyzkum.cz/storage/att/E6EF7938F0E854BAE520AC119FB22E8D/Prevodnik_oboru_Frascati.pdf">converter</a>)

    30105 - Physiology (including cytology)<br>30201 - Cardiac and Cardiovascular systems

Completed project evaluation

  • Provider evaluation

    V - Vynikající výsledky projektu (s mezinárodním významem atd.)

  • Project results evaluation

    Increased angiotensin II concentrations together with increased vascular sensitivity are the main mech.responsible for the development of hypertension in prehypertensive Ren-2 transgenic rats.Angiotensin 1-7 partilly compensates the advers effects ang.II

Solution timeline

  • Realization period - beginning

    Jan 1, 2004

  • Realization period - end

    Jan 1, 2006

  • Project status

    U - Finished project

  • Latest support payment

Data delivery to CEP

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

  • Data delivery code

    CEP07-MZ0-NR-U/06:2

  • Data delivery date

    Aug 8, 2007

Finance

  • Total approved costs

    3,213 thou. CZK

  • Public financial support

    3,188 thou. CZK

  • Other public sources

    25 thou. CZK

  • Non public and foreign sources

    0 thou. CZK