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NR9194

Regulation of the Nitric Oxide during Cardiac operation with Cardiopulmonary Bypass

Public support

  • Provider

    Ministry of Health

  • Programme

    Branch programm of research of the Ministry of Health

  • Call for proposals

    VaV pro Ministerstvo zdravotnictví 4 (SMZ02007NR)

  • Main participants

  • Contest type

    VS - Public tender

  • Contract ID

    NR9194-3/2007

Alternative language

  • Project name in Czech

    Regulace oxydu dusnatého u srdečních operací v mimotělním oběhu

  • Annotation in Czech

    Zhodnocení exhalace NO chemiluminiscencí jako klinicky vhodného prostředku k hodnocení stavu endotelové dysfunkce po srdečních operacích v mimotělním oběhu s navržením strategie omezující tuto cévní reakci. Zhodnocení exprese eNOS,iNOS ve vzorcích myokardu za standardní situace operace srdce a po farmakologickém prekonditioningu (nitráty, L-arginin).

Scientific branches

  • R&D category

    NV - Nonindustrial research (Applied research excluded Industrial research)

  • CEP classification - main branch

    EB - Genetics and molecular biology

  • CEP - secondary branch

    EC - Immunology

  • CEP - another secondary branch

  • OECD FORD - equivalent branches <br>(according to the <a href="http://www.vyzkum.cz/storage/att/E6EF7938F0E854BAE520AC119FB22E8D/Prevodnik_oboru_Frascati.pdf">converter</a>)

    10603 - Genetics and heredity (medical genetics to be 3)<br>10604 - Reproductive biology (medical aspects to be 3)<br>10605 - Developmental biology<br>10608 - Biochemistry and molecular biology<br>10609 - Biochemical research methods<br>30101 - Human genetics<br>30102 - Immunology

Completed project evaluation

  • Provider evaluation

    V - Vynikající výsledky projektu (s mezinárodním významem atd.)

  • Project results evaluation

    Perioperative monitoring of exhaled NO during cardiac surgery differenciates patients indicated for the treatment of inhaled NO. Preoperative remote ischemic preconditioning using upper limb augments myocardial protection during surgery.

Solution timeline

  • Realization period - beginning

    Jan 1, 2007

  • Realization period - end

    Dec 31, 2009

  • Project status

    U - Finished project

  • Latest support payment

    Dec 18, 2009

Data delivery to CEP

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

  • Data delivery code

    CEP10-MZ0-NR-U/03:3

  • Data delivery date

    Apr 27, 2011

Finance

  • Total approved costs

    2,389 thou. CZK

  • Public financial support

    2,149 thou. CZK

  • Other public sources

    240 thou. CZK

  • Non public and foreign sources

    0 thou. CZK