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NR9273

Local and systemic pathogenetic role of "DASH system" molecules in rheumatoid arthritis

Public support

  • Provider

    Ministry of Health

  • Programme

    Branch programm of research of the Ministry of Health

  • Call for proposals

    VaV pro Ministerstvo zdravotnictví 4 (SMZ02007NR)

  • Main participants

  • Contest type

    VS - Public tender

  • Contract ID

    NR9273-3/2007

Alternative language

  • Project name in Czech

    Význam molekul "DASH systému" v lokálních a systémových patogenetických procesech revmatoidní artritidy

  • Annotation in Czech

    Projekt hledá funkční vztahy mezi Dipeptidylpeptidase-IV aktivitou a/nebo strukturou homologními molekulami, jejich biologicky aktivními substráty a odpovídajícími receptory, relevantní pro vznik, rozvoj, diagnostiku a léčbu revmatoidní artritidy

Scientific branches

  • R&D category

    NV - Nonindustrial research (Applied research excluded Industrial research)

  • CEP classification - main branch

    FE - Other fields of internal medicine

  • CEP - secondary branch

  • CEP - another secondary branch

  • OECD FORD - equivalent branches <br>(according to the <a href="http://www.vyzkum.cz/storage/att/E6EF7938F0E854BAE520AC119FB22E8D/Prevodnik_oboru_Frascati.pdf">converter</a>)

    30217 - Urology and nephrology<br>30218 - General and internal medicine<br>30219 - Gastroenterology and hepatology<br>30220 - Andrology

Completed project evaluation

  • Provider evaluation

    V - Vynikající výsledky projektu (s mezinárodním významem atd.)

  • Project results evaluation

    Canonical dipeptidyl peptidase -IV (DPP-IV) represedens a major source of DPP-IV activity in blood plasma, synovial fluid, and the respective mononuclear cells. It might participate on rheumatoid arthritis pathogenesis via degradation of SDF-1alfa.

Solution timeline

  • Realization period - beginning

    Jan 1, 2007

  • Realization period - end

    Dec 31, 2009

  • Project status

    U - Finished project

  • Latest support payment

    Dec 18, 2009

Data delivery to CEP

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

  • Data delivery code

    CEP10-MZ0-NR-U/03:3

  • Data delivery date

    Apr 27, 2011

Finance

  • Total approved costs

    3,538 thou. CZK

  • Public financial support

    3,489 thou. CZK

  • Other public sources

    45 thou. CZK

  • Non public and foreign sources

    4 thou. CZK