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NR9443

Genetic variability of pentose phosphate pathway as a modulating factor of the onset and progression of diabetic nephropathy

Public support

  • Provider

    Ministry of Health

  • Programme

    Branch programm of research of the Ministry of Health

  • Call for proposals

    VaV pro Ministerstvo zdravotnictví 4 (SMZ02007NR)

  • Main participants

  • Contest type

    VS - Public tender

  • Contract ID

    NR9443-3/2007

Alternative language

  • Project name in Czech

    Genetická variabilita enzymů pentózového cyklu jako faktor modulující nástup a progresi diabetické nefropatie

  • Annotation in Czech

    Projekt si klade za cíl pomocí genetického vyšetření variability v genech pro transketolázu a transaldolázu optimalizovat časnou diagnostiku diabetické nefropatie a umožnit individualizaci sledování diabetiků a případně i radikálnosti terapie.

Scientific branches

  • R&D category

    NV - Nonindustrial research (Applied research excluded Industrial research)

  • CEP classification - main branch

    FB - Endocrinology, diabetology, metabolism, nutrition

  • CEP - secondary branch

    EB - Genetics and molecular biology

  • CEP - another secondary branch

  • OECD FORD - equivalent branches <br>(according to the <a href="http://www.vyzkum.cz/storage/att/E6EF7938F0E854BAE520AC119FB22E8D/Prevodnik_oboru_Frascati.pdf">converter</a>)

    10603 - Genetics and heredity (medical genetics to be 3)<br>10604 - Reproductive biology (medical aspects to be 3)<br>10605 - Developmental biology<br>10608 - Biochemistry and molecular biology<br>10609 - Biochemical research methods<br>30101 - Human genetics<br>30202 - Endocrinology and metabolism (including diabetes, hormones)

Completed project evaluation

  • Provider evaluation

    V - Vynikající výsledky projektu (s mezinárodním významem atd.)

  • Project results evaluation

    Functional thiamine deficiency due to its limited intracellular availability seems to be a dominant abnormality in diabetic patients.

Solution timeline

  • Realization period - beginning

    Jan 1, 2007

  • Realization period - end

    Dec 31, 2009

  • Project status

    U - Finished project

  • Latest support payment

    Dec 18, 2009

Data delivery to CEP

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

  • Data delivery code

    CEP10-MZ0-NR-U/03:3

  • Data delivery date

    Apr 27, 2011

Finance

  • Total approved costs

    3,846 thou. CZK

  • Public financial support

    3,846 thou. CZK

  • Other public sources

    0 thou. CZK

  • Non public and foreign sources

    0 thou. CZK