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NS9703

Novel approach to blood pressure control and organ protection- intervention to renin-angiotensin and endothelin systems

Public support

  • Provider

    Ministry of Health

  • Programme

    Departmental Programme of Research and Development - MH II from 2008 to 2011

  • Call for proposals

    VaV pro Ministerstvo zdravotnictví II 1 (SMZ0200801)

  • Main participants

  • Contest type

    VS - Public tender

  • Contract ID

    NS9703-4/2008

Alternative language

  • Project name in Czech

    Nové farmakologické přístupy k léčbě hypertenze - kombinované zásahy do renin-angiotenzinového a endotelinového systému

  • Annotation in Czech

    Budou studovány účinky dvou nových antihypertenzně působících látek (aliskiren a DARA) zasahujících do renin-angiotensinového (RAS) a endotelinového systému (ET) na modelu transgenních potkanů pro myší reninový gen.

Scientific branches

  • R&D category

    NV - Nonindustrial research (Applied research excluded Industrial research)

  • CEP classification - main branch

    FA - Cardiovascular diseases including cardio-surgery

  • CEP - secondary branch

    ED - Physiology

  • CEP - another secondary branch

    FR - Pharmacology and apothecary chemistry

  • OECD FORD - equivalent branches <br>(according to the <a href="http://www.vyzkum.cz/storage/att/E6EF7938F0E854BAE520AC119FB22E8D/Prevodnik_oboru_Frascati.pdf">converter</a>)

    30104 - Pharmacology and pharmacy<br>30105 - Physiology (including cytology)<br>30201 - Cardiac and Cardiovascular systems

Completed project evaluation

  • Provider evaluation

    U - Uspěl podle zadání (s publikovanými či patentovanými výsledky atd.)

  • Project results evaluation

    Treatment with alikiren in TGR rats demonstrated better nephro - and cardioprotective effects compared to losartan.

Solution timeline

  • Realization period - beginning

    Jul 1, 2008

  • Realization period - end

    Dec 31, 2011

  • Project status

    U - Finished project

  • Latest support payment

    Aug 8, 2011

Data delivery to CEP

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

  • Data delivery code

    CEP12-MZ0-NS-U/09:3

  • Data delivery date

    Oct 31, 2013

Finance

  • Total approved costs

    3,253 thou. CZK

  • Public financial support

    3,253 thou. CZK

  • Other public sources

    0 thou. CZK

  • Non public and foreign sources

    0 thou. CZK