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NS9775

The role of probiotics and dental plaque bacteria in development of atheroscklerotic changes in clinical praxis and experimental model

Public support

  • Provider

    Ministry of Health

  • Programme

    Departmental Programme of Research and Development - MH II from 2008 to 2011

  • Call for proposals

    VaV pro Ministerstvo zdravotnictví II 1 (SMZ0200801)

  • Main participants

  • Contest type

    VS - Public tender

  • Contract ID

    NS9775-4/2008

Alternative language

  • Project name in Czech

    Úloha probiotik a bakterií zubního povlaku v rozvoji aterosklerotických změn u pacientů s chronickou parodontitidou a v experimentálním modelu

  • Annotation in Czech

    Anotace I: Úloha probiotik a bakterií zubního povlaku v rozvoji aterosklerózy Anotace III: Pacienti s chronickou parodontitidou a riziko aterosklerózy Anotace II: Experimentální modely aterosklerózy

Scientific branches

  • R&D category

    NV - Nonindustrial research (Applied research excluded Industrial research)

  • CEP classification - main branch

    FF - ENT (ie. ear, nose, throat), ophthalmology, dentistry

  • CEP - secondary branch

    FN - Epidemiology, infection diseases and clinical immunology

  • CEP - another secondary branch

  • OECD FORD - equivalent branches <br>(according to the <a href="http://www.vyzkum.cz/storage/att/E6EF7938F0E854BAE520AC119FB22E8D/Prevodnik_oboru_Frascati.pdf">converter</a>)

    30206 - Otorhinolaryngology<br>30207 - Ophthalmology<br>30208 - Dentistry, oral surgery and medicine<br>30302 - Epidemiology<br>30303 - Infectious Diseases

Completed project evaluation

  • Provider evaluation

    V - Vynikající výsledky projektu (s mezinárodním významem atd.)

  • Project results evaluation

    Polymortphisms in metalloproteinase 8, TLR 2 and TLR 9 are not associated with chronic periodontitis in humans. Normal intestinal flora has protective effect on atherosclerosis formation in a fat-rich diet in hypercholesterolemic rats.

Solution timeline

  • Realization period - beginning

    Jul 1, 2008

  • Realization period - end

    Dec 31, 2011

  • Project status

    U - Finished project

  • Latest support payment

    Aug 8, 2011

Data delivery to CEP

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

  • Data delivery code

    CEP12-MZ0-NS-U/09:3

  • Data delivery date

    Oct 31, 2013

Finance

  • Total approved costs

    6,348 thou. CZK

  • Public financial support

    6,348 thou. CZK

  • Other public sources

    0 thou. CZK

  • Non public and foreign sources

    0 thou. CZK