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NT11225

Diagnosis of Alzheimer disease based on detections of complexes of amyloid beta peptide and of some endogenous substances in cerebrospinal fluid

Public support

  • Provider

    Ministry of Health

  • Programme

    Ministry of Health?s Departmental Research and Development Programme III

  • Call for proposals

    VaV pro Ministerstvo zdravotnictví III 1 (SMZ0201001)

  • Main participants

  • Contest type

    VS - Public tender

  • Contract ID

    NT11225-4/2010

Alternative language

  • Project name in Czech

    Diagnostika Alzheimerovy nemoci založená na detekci komplexů peptidu amyloidu beta s některými endogenními látkami v cerebrospinální tekutině

  • Annotation in Czech

    Po zavedení nových citlivých metod (ELISA a senzory s povrchovými plazmony) budou v mozkomíšním moku dementních a nedementních lidí testovány hladiny dvou komplexů peptidu amyloidu beta (s mitochondriálním enzymem 17beta-hydroxysteroidovou dehydrogenázoutypu 10 a proteinem tau). Pomocí kitů budou dále stanoveny hladiny tripletu (amyloid beta 1-42, celkový tau a fosforylovaný tau).

Scientific branches

  • R&D category

    NV - Nonindustrial research (Applied research excluded Industrial research)

  • CEP classification - main branch

    FH - Neurology, neuro-surgery, nuero-sciences

  • CEP - secondary branch

  • CEP - another secondary branch

  • OECD FORD - equivalent branches <br>(according to the <a href="http://www.vyzkum.cz/storage/att/E6EF7938F0E854BAE520AC119FB22E8D/Prevodnik_oboru_Frascati.pdf">converter</a>)

    30103 - Neurosciences (including psychophysiology)<br>30210 - Clinical neurology

Completed project evaluation

  • Provider evaluation

    V - Vynikající výsledky projektu (s mezinárodním významem atd.)

  • Project results evaluation

    In accord with the annotations and the terms, the project led to the introduction of new biological markers for detection of dementia Alzheimer's type. The publications with IF in CR and abroad with dedication to IGA MZ exceeded the project plans.

Solution timeline

  • Realization period - beginning

    Sep 1, 2010

  • Realization period - end

    Dec 31, 2013

  • Project status

    U - Finished project

  • Latest support payment

    Mar 26, 2013

Data delivery to CEP

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

  • Data delivery code

    CEP14-MZ0-NT-U/04:2

  • Data delivery date

    Sep 2, 2014

Finance

  • Total approved costs

    9,657 thou. CZK

  • Public financial support

    9,657 thou. CZK

  • Other public sources

    0 thou. CZK

  • Non public and foreign sources

    0 thou. CZK