All

What are you looking for?

All
Projects
Results
Organizations

Quick search

  • Projects supported by TA ČR
  • Excellent projects
  • Projects with the highest public support
  • Current projects

Smart search

  • That is how I find a specific +word
  • That is how I leave the -word out of the results
  • “That is how I can find the whole phrase”
NT12452

The significance of micro (mi)RNA in etiopathogenesis of myositis: application of miRNA expression profiling for monitoring of disease activity

Public support

  • Provider

    Ministry of Health

  • Programme

    Ministry of Health?s Departmental Research and Development Programme III

  • Call for proposals

    VaV pro Ministerstvo zdravotnictví III 2 (SMZ0201101)

  • Main participants

  • Contest type

    VS - Public tender

  • Contract ID

    NT12452-4/2011

Alternative language

  • Project name in Czech

    Význam micro (mi)RNA v etiopatogenezi myozitidy a využití expresního profilování miRNA ke sledování aktivity onemocnění.

  • Annotation in Czech

    Identifikace disproporcionálně exprimovaných miRNA v periferních krevních buňkách a ve svalových buňkách u pacientů s polymyozitidou a dermatomyozitidou za účelem zjištění jejich podílu na patogenezi onemocnění. Využití kvantitativního stanovení abnormálně produkovaných miRNA k hodnocení onemocnění, jeho aktivity a prognózy.

Scientific branches

  • R&D category

    NV - Nonindustrial research (Applied research excluded Industrial research)

  • CEP classification - main branch

    EB - Genetics and molecular biology

  • CEP - secondary branch

  • CEP - another secondary branch

  • OECD FORD - equivalent branches <br>(according to the <a href="http://www.vyzkum.cz/storage/att/E6EF7938F0E854BAE520AC119FB22E8D/Prevodnik_oboru_Frascati.pdf">converter</a>)

    10603 - Genetics and heredity (medical genetics to be 3)<br>10604 - Reproductive biology (medical aspects to be 3)<br>10605 - Developmental biology<br>10608 - Biochemistry and molecular biology<br>10609 - Biochemical research methods<br>30101 - Human genetics

Completed project evaluation

  • Provider evaluation

    V - Vynikající výsledky projektu (s mezinárodním významem atd.)

  • Project results evaluation

    This study has shown that patients suffering from myositis have significantly changed expression profile of miRNA molecules. Significant changes were found in serum, PBMCs and muscle biopsies of patients.Test may help with a rapid screening of myositis.

Solution timeline

  • Realization period - beginning

    Jun 1, 2011

  • Realization period - end

    Dec 31, 2014

  • Project status

    U - Finished project

  • Latest support payment

    Mar 21, 2014

Data delivery to CEP

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

  • Data delivery code

    CEP15-MZ0-NT-U/05:3

  • Data delivery date

    Dec 14, 2015

Finance

  • Total approved costs

    6,490 thou. CZK

  • Public financial support

    6,490 thou. CZK

  • Other public sources

    0 thou. CZK

  • Non public and foreign sources

    0 thou. CZK