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NT14350

Pathogenesis of hyperdiploid leukaemias

Public support

  • Provider

    Ministry of Health

  • Programme

    Ministry of Health?s Departmental Research and Development Programme III

  • Call for proposals

    VaV pro Ministerstvo zdravotnictví III 4 (SMZ0201301)

  • Main participants

  • Contest type

    VS - Public tender

  • Contract ID

    NT14350-3/2013

Alternative language

  • Project name in Czech

    Patogenese hyperdiploidních leukemií

  • Annotation in Czech

    V rámci předkládaného projektu budeme analysovat buňky hyperdiploidních akutních lymfoblastických leukemií. Získáme data o charakteru genetických a funkčních změn typických pro tento nejčastější podtyp dětských leukemii a o jeho patogenesi. To může vést ke správnější stratifikaci a terapii těchto pacientů.

Scientific branches

  • R&D category

    NV - Nonindustrial research (Applied research excluded Industrial research)

  • CEP classification - main branch

    FD - Oncology and haematology

  • CEP - secondary branch

    FG - Paediatrics

  • CEP - another secondary branch

    EB - Genetics and molecular biology

  • OECD FORD - equivalent branches <br>(according to the <a href="http://www.vyzkum.cz/storage/att/E6EF7938F0E854BAE520AC119FB22E8D/Prevodnik_oboru_Frascati.pdf">converter</a>)

    10603 - Genetics and heredity (medical genetics to be 3)<br>10604 - Reproductive biology (medical aspects to be 3)<br>10605 - Developmental biology<br>10608 - Biochemistry and molecular biology<br>10609 - Biochemical research methods<br>30101 - Human genetics<br>30204 - Oncology<br>30205 - Hematology<br>30209 - Paediatrics

Completed project evaluation

  • Provider evaluation

    V - Vynikající výsledky projektu (s mezinárodním významem atd.)

  • Project results evaluation

    The research is done on hyperdiploid ALL. In the group of patients heterogeneity was found. The differences in DNA index may be a predictor of treatment success. Preleukemic clones were discovered in umbilical blood. Further analysis of these continues.

Solution timeline

  • Realization period - beginning

    May 1, 2013

  • Realization period - end

    Dec 31, 2015

  • Project status

    U - Finished project

  • Latest support payment

    Mar 20, 2015

Data delivery to CEP

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

  • Data delivery code

    CEP16-MZ0-NT-U/02:1

  • Data delivery date

    Dec 19, 2016

Finance

  • Total approved costs

    6,731 thou. CZK

  • Public financial support

    6,731 thou. CZK

  • Other public sources

    0 thou. CZK

  • Non public and foreign sources

    0 thou. CZK