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Biomedical photonic devices for advanced medicinal diagnostics and therapy

Public support

  • Provider

    Ministry of Health

  • Programme

    Programme to support medical applied research in 2015 to 2022

  • Call for proposals

    Zdravotnický AV 1 (SMZ0201501)

  • Main participants

    Fakultní nemocnice Hradec Králové

  • Contest type

    VS - Public tender

  • Contract ID

    15-33459A

Alternative language

  • Project name in Czech

    Biomedicínská fotonická zařízení pro pokročilou lékařskou diagnostiku a terapii

  • Annotation in Czech

    Navrhovaný projekt zahrnuje vytvoření nového systému z optických vláken pro lokální monitorování, snímání a modifikaci substrátu. Materiál pro zavedení do živé tkáně (in-vivo experiment) bude navržen biologicky rozložitelný a biologicky kompatibilní. Tím se zabrání riziku spojenému s použitím konvenčního vlákna z křemenného skla. Pro základ výzkumu bude použita polymerní směs a polymerní sítě. Následně bude vyvinut materiál pro konstrukci optického vlákna a jeho spojení s laserovými zdroji a detektory. Povrch optických vláken bude vyvíjen s funkcionalizovanou citlivou vrstvou pro zavedení možnosti pro chemické analýzy in-vivo. Bezpečnost a biokompatibilita vyvinutého systému bude testována v preklinických podmínkách. Projekt kombinuje odborníky z různých oblastí výzkumu, jsou kompletně pokryty všechny fáze projektu.

Scientific branches

  • R&D category

    AP - Applied research

  • CEP classification - main branch

    EI - Biotechnology and bionics

  • CEP - secondary branch

    BH - Optics, masers and lasers

  • CEP - another secondary branch

    FS - Medical facilities, apparatus and equipment

  • OECD FORD - equivalent branches <br>(according to the <a href="http://www.vyzkum.cz/storage/att/E6EF7938F0E854BAE520AC119FB22E8D/Prevodnik_oboru_Frascati.pdf">converter</a>)

    10306 - Optics (including laser optics and quantum optics)<br>20601 - Medical engineering<br>20602 - Medical laboratory technology (including laboratory samples analysis; diagnostic technologies) (Biomaterials to be 2.9 [physical characteristics of living material as related to medical implants, devices, sensors])<br>20801 - Environmental biotechnology<br>20802 - Bioremediation, diagnostic biotechnologies (DNA chips and biosensing devices) in environmental management<br>20803 - Environmental biotechnology related ethics<br>20901 - Industrial biotechnology<br>20902 - Bioprocessing technologies (industrial processes relying on biological agents to drive the process) biocatalysis, fermentation<br>20903 - Bioproducts (products that are manufactured using biological material as feedstock) biomaterials, bioplastics, biofuels, bioderived bulk and fine chemicals, bio-derived novel materials<br>30401 - Health-related biotechnology<br>30402 - Technologies involving the manipulation of cells, tissues, organs or the whole organism (assisted reproduction)<br>30403 - Technologies involving identifying the functioning of DNA, proteins and enzymes and how they influence the onset of disease and maintenance of well-being (gene-based diagnostics and therapeutic interventions [pharmacogenomics, gene-based therapeutics])<br>30404 - Biomaterials (as related to medical implants, devices, sensors)<br>30405 - Medical biotechnology related ethics<br>40401 - Agricultural biotechnology and food biotechnology<br>40402 - GM technology (crops and livestock), livestock cloning, marker assisted selection, diagnostics (DNA chips and biosensing devices for the early/accurate detection of diseases) biomass feedstock production technologies, biopharming<br>40403 - Agricultural biotechnology related ethics

Completed project evaluation

  • Provider evaluation

    V - Vynikající výsledky projektu (s mezinárodním významem atd.)

  • Project results evaluation

    Project has fulfilled all expected plans in both aspects: a) number of scientific publications (Jimp 11+1) and b) practical outputs (1 patent, 2 prototypes). Topic of the project – the development of biodegradable materials for optical transfer – is highly attractive especially from technological site. Number of realized experiments showed the perspectives of this development. Very strong outcome of the projects is also multi-specialization cooperation of activities in material engineering, an optical technology and biomedical testing. Project allowed the research of the controlled surface and structural modification including its influence on various biocompatible and biodegradable materials for the development of the unique sensors and probes with the use in medicine and biology. Completely new and promising way was directed to biodegradable fibers from soft glass. This direction seems to be very promising due to high optical quality and first successful tests with biodegradable fi

Solution timeline

  • Realization period - beginning

    May 1, 2015

  • Realization period - end

    Dec 31, 2018

  • Project status

    U - Finished project

  • Latest support payment

    Jun 28, 2018

Data delivery to CEP

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

  • Data delivery code

    CEP19-MZ0-NV-U/01:1

  • Data delivery date

    Jun 28, 2019

Finance

  • Total approved costs

    15,728 thou. CZK

  • Public financial support

    15,553 thou. CZK

  • Other public sources

    175 thou. CZK

  • Non public and foreign sources

    0 thou. CZK