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Sentinel testing survey of plasmid-mediated (transferable) colistin resistance among Enterobacteriaceae in the Czech Republic

Public support

  • Provider

    Ministry of Health

  • Programme

    Programme to support medical applied research in 2015 to 2022

  • Call for proposals

    Zdravotnický AV 4 (SMZ0201800001)

  • Main participants

    Univerzita Karlova / 2. lékařská fakulta

  • Contest type

    VS - Public tender

  • Contract ID

    NV18-09-00254

Alternative language

  • Project name in Czech

    Sentinelová studie výskytu na plazmid vázané (přenositelné) rezistence ke kolistinu u Enterobacteriaceae v České republice

  • Annotation in Czech

    Projekt je sentinelovou studií zaměřenou na vyhledávání Enterobacteriaceae s přenositelnou na plazmid vázanou rezistencí ke kolistinu (rezervnímu antibiotiku v humánní medicíně avšak antibiotiku používaném i ve veterinárním sektoru) u hospitalizovaných pacientů a cestovatelů, potravinových zvířat a jejich mase a v prostředí.

Scientific branches

  • R&D category

    AP - Applied research

  • OECD FORD - main branch

    30302 - Epidemiology

  • OECD FORD - secondary branch

    40301 - Veterinary science

  • OECD FORD - another secondary branch

    10606 - Microbiology

  • CEP - equivalent branches <br>(according to the <a href="http://www.vyzkum.cz/storage/att/E6EF7938F0E854BAE520AC119FB22E8D/Prevodnik_oboru_Frascati.pdf">converter</a>)

    EE - Microbiology, virology<br>FN - Epidemiology, infection diseases and clinical immunology<br>GJ - Diseases and animal vermin, veterinary medicine

Completed project evaluation

  • Provider evaluation

    V - Vynikající výsledky projektu (s mezinárodním významem atd.)

  • Project results evaluation

    The authors have demonstrated the relatively rare presence of plasmid-linked colistin resistance genes in hospitalized patients and healthy individuals with and without a travel history. On the contrary, they found its higher prevalence in meat and meat products of both domestic and foreign production. This fact indicates a potential risk to consumers. The result of the project is a narrower definition of risk groups within our population, for which it is necessary to consider the implementation of preventive screening for the occurrence of the above-described resistance to colistin. All the main objectives of the original project application were met at a high level. As a result of the project, six original articles, some of which are in Q1 or even D1 of the research field according to WoS, have been published. The total impact factor of all publications is approaching 30 and both qualitatively and quantitatively the authors have surpassed the original publication plan. In addition, t

Solution timeline

  • Realization period - beginning

    May 1, 2018

  • Realization period - end

    Dec 31, 2021

  • Project status

    U - Finished project

  • Latest support payment

    Apr 6, 2020

Data delivery to CEP

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

  • Data delivery code

    CEP22-MZ0-NV-U

  • Data delivery date

    Jun 30, 2022

Finance

  • Total approved costs

    10,491 thou. CZK

  • Public financial support

    10,491 thou. CZK

  • Other public sources

    0 thou. CZK

  • Non public and foreign sources

    0 thou. CZK